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Genetic Variants and Strains of the Laboratory Mouse - Mary F. Lyon

Genetic Variants and Strains of the Laboratory Mouse

By: Mary F. Lyon (Editor), Sohaila Rastan (Editor), S. D. M. Brown (Editor)

Hardcover Published: 25th January 1996
ISBN: 9780198548690
Number Of Pages: 870

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This book constitutes a unique source of information on mouse variants and is an essential reference for those many biologists who use mouse genetic strains and variants in their research. The third edition reflects the great expansion of knowledge in the field in recent years, and includes new chapters on transgenics, simple sequence polymorphisms, and recombinant cogenic strains. Data in other chapters have increased several fold and the book is double in length. As in earlier editions, the main chapter provides a catalogue of all known mouse genes. Other chapters give tables of DNA probes and RFLPs, and of mapped mouse - human homologies. Genetic maps are supported by a large table of data on recombinant fractions. There are catalogues of known chromosome aberrations, of inbred strains, and of wild-derived strains. Valuable tables give strain distribution patterns of alleles in recombinant inbred strains. Three very important chapters give the latest rules for nomenclature of genes, inbred strains, and chromosome aberrations.

Industry Reviews

`These volumes have been prepared on behalf of the Committee on Standardized Genetic Nomenclature for mice and provide almost all the information you might need about mouse genetics. Extensive up-to-date references are provided throughout. Access to these volumes is a must for those requiring information on the current state of mouse genetics.' Colin Hetherington, Laboratory Animals, No. 30, 1996 `a welcome update to the book originally edited by Margaret Green' Annals of Human Genetics, Vol. 61 - 1997 `an exhaustive compilation of known genetic variants and inbred strains of the mouse ... This invaluable book is a must in any biomedical reference library. The book is of immense interest to mouse geneticists as well as human geneticists. This book not only serves as an easily accessible resource of some of what is available on the Internet but it also includes chapters on related topics. This book serves as an excellent supplement and a ready-to-use hard copy of recent data on mouse genetics ... should meet the needs of a range of users, including students, research faculty, and industrial scientists across various fields.' Mitzi Nagarkatti, Virginia Polytechnic Institute and State University, Journal of Heredity 89(1)

1: Rules and guidelines for gene nomenclature 2: Catalog of mutant genes and polymorphic loci 3: Retroviral and cancer-related genes 4: Linkage map 5: Map of the t-complex 6: Recombination percentages and chromosomal assignments 7: Linkage and synteny homologies in mouse and man 8: DNA polymorphisms 9: Highly repeated DNA families in the genome of Mus musculus 10: Rules for nomenclature of chromosome anomalies 11: Standard normal chromosomes 12: Chromosomal variants 13: Maps of chromosomal variants 14: Rules for nomenclature of inbred strains 15: Origins and characteristics of inbred strains of mice 16: The laboratory mouse and its wild relatives 17: Strain distribution of polymorphic variants 18: Recombinant inbred strains 19: Recombinant congenic strains - genetic composition 20: SSLP/Microsatellite genetic linkage map of the mouse 21: Principles and methods of transgenic mutagenesis 22: Subline codes for holders and producers

ISBN: 9780198548690
ISBN-10: 0198548699
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 870
Published: 25th January 1996
Publisher: Oxford University Press
Country of Publication: GB
Dimensions (cm): 32.0 x 20.3  x 10.3
Weight (kg): 3.71
Edition Number: 3
Edition Type: Revised