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Genetic Mapping of Disease Genes - Ivar-Harry Pawlowtzki

Genetic Mapping of Disease Genes

Hardcover

Published: 19th August 1997
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A state-of-the-art reference, Genetic Mapping of Disease Genes presents a detailed account of the new methodical approaches to gene mapping. It provides completely up-to-date information and comprehensive coverage of research in this field, and includes contributions from the leading experts. The book gives a broad overview of the genetic mapping involved in inherited diseases and discusses the shortcomings of established mapping procedures.
The book will be essential reading for all researchers and postgraduate research students in molecular genetics, clinical genetics, and molecular biology, but also those involved in ophthalmology, public health, medical statistics, and mathematics.
Key Features
* The volume covers:
* Introduction and History
* Linkage in Dominant Recessive and Oligogenic Disease
* Model Free (Non-Parametric) Methods
* Tools (for Gene Mapping)
* Applications

"These contributions, from some of the most eminent geneticists of our day, are dazzlingly heterogenous in both style and content. They range from the thorough and methodical to the allusive and almost whimsical, from a fascinating account of the earliest history of linkage analysis to descriptions of novel methods whose status in the field is as yet unclear...I would recommend this book to anyone with an interest in this field." --ANNALS OF HUMAN GENETICS

Introduction and History
Introduction
The Early History of the Statistical Estimation of Linkage
Linkage in Dominant, Recessive, and Polygenic Disease
Oligogenic Linkage and Map Integration
Genetic Mapping in Complex Disorders
Recessive Disease and Allelic Association
Mutation-Selection-Equilibria
Simple Likelihood and Probability
Calculations for Linkage Analysis
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9780122327353
ISBN-10: 0122327357
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 288
Published: 19th August 1997
Publisher: Elsevier Science Publishing Co Inc
Country of Publication: US
Dimensions (cm): 22.9 x 15.2  x 1.93
Weight (kg): 0.62