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Gene-Based Therapies for Cancer : Current Cancer Research - Jack A. Roth

Gene-Based Therapies for Cancer

Current Cancer Research

By: Jack A. Roth (Editor)


Published: 4th August 2010
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Cancer gene therapy is a novel therapy that targets the underlying genetic defects in the cancer cell. Progress in this field has been rapid and gene therapy promises to further extend personalized cancer treatment. In this volume leading experts have contributed their experience in developing gene therapies for a variety of cancers. Translational gene therapy approaches are emphasized. Chapters include discussions of specific gene delivery technologies as well as their application to various cancers with extensive discussions of ongoing clinical trials. This information should be useful to both students, fellows, and experienced scientists with an interest in this rapidly developing area.

RNAi: A New Paradigm in Cancer Gene Therapyp. 1
Gene-Based Therapy for Cancer: Brain Tumorsp. 17
Gene Therapy of Prostate Cancerp. 33
siRNA Versus shRNA for Personalized Cancer Therapy: Mechanisms and Applicationsp. 51
Tumor Suppressor Gene Therapyp. 63
Targeted Oncolytic Adenovirus for Human Cancer Therapy: Gene-Based Therapies for Cancerp. 79
Gene Therapy for Malignant Pleural Mesotheliomap. 95
Mesenchymal Stem/Stromal Cells as Cellular Vehicles for Tumor Targetingp. 113
Retargeting Adenovirus for Cancer Gene Therapyp. 141
Lentiviruses: Vectors for Cancer Gene Therapyp. 155
Interleukin-24 Gene Therapy for Melanomap. 181
Herpes Simplex Virus 1 for Cancer Therapyp. 203
Telomerase as a Target for Cancer Therapeuticsp. 231
Gene Therapy for Sarcomap. 251
Indexp. 269
Table of Contents provided by Ingram. All Rights Reserved.

ISBN: 9781441961013
ISBN-10: 1441961011
Series: Current Cancer Research
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 278
Published: 4th August 2010
Publisher: Springer-Verlag New York Inc.
Country of Publication: US
Dimensions (cm): 23.5 x 15.5  x 1.91
Weight (kg): 0.66