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Frontiers in Molecular Toxicology : American Chemical Society Publication - Lawrence J. Marnett

Frontiers in Molecular Toxicology

American Chemical Society Publication

By: Lawrence J. Marnett (Editor)

Paperback Published: 5th May 1992
ISBN: 9780841224285
Number Of Pages: 294

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Provides concise, up-to-date articles highlighting the most recent advances in mechanisms of toxicology and the methods for studying them. Examines chemical approaches to the solution of toxicologically interesting problems. Originally published in Chemical Research in Toxicology, the articles convey the opportunity and excitement that exists at the interface of chemistry and toxicology. Twenty-one articles are grouped into four broad categories: Toxic Agents and their Actions; Enzymes of Activation, Inactivation, and Repair; Physical Methods; and Macromolecular Modification.

Role of the Terminal Olefin, 2-n-Propyl-4-pentenoic Acid
Photochemistry of the Psoralens
Mechanisms of 3-Methylindole Pneumotoxicity
Redox Chemistry of Anthracycline Antitumor Drugs and Use of Captodative Radicals as Tools for its Elucidation and Control
The Fecapentaenes, Potent Mutagens from Human Feces
Mammalian Synthesis of Nitrite, Nitrate, Nitric Oxide, and N-Nitrosating Agents
Mechanisms of Immunotoxicity to Isocyanates
Mechanisms of Drug-Induced Lupus
Molecular and Biochemical Mechanisms of Chemically Induced Nephrotoxicity: A Review
Oxidation of Toxic and Carcinogenic Chemicals by Human Cytochrome P-450 Enzymes
Glutathione S-Transferases: Reaction Mechanism, Structure, and Function
Isolation and Purification of UDP-Glucuronosyltransferases
DNA Repair
Applications of NMR Spectroscopy to Studies of Reactive Intermediates and Their Interactions with Nucleic Acids
Fluorescence Line Narrowing: A High-Resolution Window on DNA and Protein Damage from Chemical Carcinogens
Site-Specifically Modified Oligodeoxynucleotides as Probes for the Structural and Biological Effects of DNA-Damaging Agents
Sequence Selectivity of DNA Covalent Modification
Covalent Bonding of the Prosthetic Heme to Protein: A Potential Mechanism for the Suicide Inactivation or Activation of Hemoproteins
Biochemical, Structural, and Functional Properties of Oxidized Low-Density Lipoprotein
Metallothionein and Other Cadmium-Binding Proteins: Recent Developments
Loss of Cancer Suppressors, a Driving Force in Carcinogenesis
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9780841224285
ISBN-10: 0841224285
Series: American Chemical Society Publication
Audience: General
Format: Paperback
Language: English
Number Of Pages: 294
Published: 5th May 1992
Publisher: American Chemical Society
Country of Publication: US
Dimensions (cm): 27.94 x 20.96  x 1.65
Weight (kg): 0.69