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From Ion Channels to Cell-to-Cell Conversations : Series of the Centro De Estudios Cientificos - Juan Carlos Seaz

From Ion Channels to Cell-to-Cell Conversations

Series of the Centro De Estudios Cientificos

By: Juan Carlos Seaz (Editor)

Hardcover Published: 30th June 1997
ISBN: 9780306456053
Number Of Pages: 504

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Ion channels allow us to see nature in all its magnificence, to hear a Bach suite, to smell the aroma of grandmother's cooking, and, in this regard, they put us in contact with the external world. These ion channels are protein molecules located in the cell membrane. In complex organisms, cells need to communicate in order to know about their metabolic status and to act in a coordinate manner. The latter is also accomplished by a class of ion channels able to pierce the lipid bilayer membranes of two adjacent cells. These intercellular channels are the functional subunits of gap junctions. Accordingly, the book is divided in two parts: the first part is dedicated to ion channels that look to the external world, and the second part is dedicated to gap junctions found at cell interfaces. This book is based on a series of symposia for a meeting on ion channels and gap junctions held in Santiago, Chile, on November 28-30, 1995. The book should be useful to graduate students taking the first steps in this field as well as a reference for the aficionado. The aim of the meeting was mainly to show the impact of various modern techniques, including cell biology, molecular biology, biophysics, and molecular- genetics techniques in the study of these ubiquitous intrinsic membrane proteins. Molecular-genetics techniques paved the road to the manipulation of the channel- forming molecules.

The Molecular Origin of Voltage Dependence in Ionic Channels
Inward Rectification by an Activation Gating Mechanism
Assembly of Shaker K-Channels from a Random Mixture of Subunits Carrying Different Mutations
New Insights into the Topography, Gating and Modulation of MaxiK Channels
Shifts of Macroscopic Current Activation in Partially Blocked Sodium Channels. Interaction between the Voltage Sensor and a [mu]-Conotoxin
[beta] Subunit Modulation of the Coupling between Charge Movement and Pore Opening in Calcium Channels
Thermodynamic Double Mutant Cycles with the Shaker K[superscript +] Channel and a Peptide Inhibitor Define the Spatial Location of Pore-Forming Residues
Barium as a Probe of the Molecular Architecture of the Pore of K[superscript +] Channels
Possible Participation of a cAMP Regulated K[superscript +] Channel from the Sea Urchin Sperm in the Speract Response
Gating and Selectivity Properties of a cAMP-Activated K[superscript +] Selective Channel from Drosophila Larval Muscle
Regulation of Ca[superscript 2+] and Na Channels in GH3 Cells by Epidermal Growth Factor
Physical State of the Nicotinic Acetylcholine Receptor Membrane and Modulation of the Receptor Channel by the Lipid Environment
Amiloride-Sensitive Na[superscript +] Channels and Human Hypertension
Anion Channels Involved in Volume Regulation: A Common Pathway for Chloride and Organic Osmolyte Permeation?
Volume-Regulated Anion Channels and Cytoskeletal Interaction
Inhibitory Responses to Odorants in Vertebrate Olfactory Neurons
Multiple Pathways in Invertebrate Visual Transduction
Structure and Function of Cell-to-Cell Channels Purified from the Lens and Hemichannels Expressed in Oocytes
Studies of Voltage Gating Gap Junctions and Hemichannels Formed by Connexin Proteins
Gap Junctions between Leukocyte and Endothelium: Expression of Connexin43 in Adherent or Activated Cells
Regulation of Gap Junctions in Rat Liver during Acute and Chronic CCl[subscript 4]-Induced Liver Injury
Cardiac Myocytes Gap Junctions: Phosphorylation of CX43 through a Protein Kinase C-Dependent Pathway
Regulation of Lens Gap Junctions
Molecular Physiology of Gap Junction Channels Formed by Connexin43
A Possible Physiological Role of the Major Intrinsic Protein of the Ocular Lens
Regulation of Smooth Muscle Activity and Gap Junctions by Sexual Hormones in the Rat Oviduct
Intercellular Calcium Signaling in Liver
Current Electrophysiological Techniques to Study Exocytosis
Index
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9780306456053
ISBN-10: 0306456052
Series: Series of the Centro De Estudios Cientificos
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 504
Published: 30th June 1997
Publisher: Springer Science+Business Media
Country of Publication: US
Dimensions (cm): 23.5 x 15.5  x 3.18
Weight (kg): 2.1

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