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Hardcover
Published: 31st July 1996
ISBN: 9780412434006
Number Of Pages: 356
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Published: 20th September 2011How is the epithelia organized? Which molecules mediate ion transport? How is an epithelia maintained? In this volume the authors discuss these and other key questions in the field and provide a clear guide to the methods used to answer them. The complexity of epithelial transport is reflected in the diverse approaches and methodologies used in its study. Written for active researchers, this book draws on the laboratory experience of leading investigators. An overview of the general principles underlying epithelial transport of ions, water and non-electrolytes is combined with guidance on practical approaches. The relative strengths and weaknesses of current methodologies are emphasized and potential pitfalls highlighted. This book should be of interest to graduates and researchers in cell biology, physiology, pharmacology, neurosciences and molecular biology.
...it will certainly attract not only the undergraduate and graduate students, but also post-doctoral fellows and established investigators. We think it will be particularly useful for clinicians and dermatologists... - Cellular and Molecular Biology
| List of contributors | |
| Preface | |
| Epithelial structure and function | p. 1 |
| Epithelial transport proteins | p. 21 |
| Epithelial polarity | p. 49 |
| Characterization of epithelial ion transport | p. 70 |
| Epithelial electrophysiology | p. 93 |
| Impedance analysis of epithelia | p. 118 |
| Measurements and interpretation of cytoplasmic ion activities | p. 146 |
| Measurements of epithelial cell volume | p. 167 |
| Methods and experimental analysis of isolated epithelial cell membranes | p. 190 |
| Methods and experimental analysis of single ion channels | p. 212 |
| Epithelial cell culture | p. 236 |
| Signaling pathways regulating ion transport in polarized cells | p. 256 |
| The cytoskeleton and epithelial function | p. 275 |
| Future perspectives: molecular biology and pathophysiology | p. 306 |
| Appendix A: Instrumentation | p. 323 |
| Appendix B: Solving simple equivalent circuits | p. 325 |
| Appendix C: A spread-sheet for marker distribution data | p. 329 |
| Index | p. 335 |
| Table of Contents provided by Blackwell. All Rights Reserved. |
ISBN: 9780412434006
ISBN-10: 0412434008
Audience:
General
Format:
Hardcover
Language:
English
Number Of Pages: 356
Published: 31st July 1996
Publisher: Chapman and Hall
Country of Publication: GB
Dimensions (cm): 24.08 x 15.65
x 2.87
Weight (kg): 0.81
Earn 746 Qantas Points
on this Book
