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Epilepsy and Sleep : Physiological and Clinical Relationships - Dudley S. Dinner

Epilepsy and Sleep

Physiological and Clinical Relationships

By: Dudley S. Dinner (Editor), Hans O. Luders (Editor)

Hardcover Published: 1st December 2000
ISBN: 9780122167706
Number Of Pages: 300

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It is well recognized that there is an intimate and reciprocal interaction between epilepsy and sleep. The book, Epilepsy and Sleep is a ground-breaking, comprehensive source for exploring this correlation and is especially timely because of the considerable growth in the understanding of the physiology underlying both sleep and epilepsy. An insightful reference, it presents many of the complex physiologic mechanisms underlying epilepsy--sleep interaction and highlights sleeping disorder symptoms that may be related to epilepsy.
The annual cost of treating epilepsy in the United States is an estimated $12.5 billion, according to a report issued January 2000 by The Epilepsy Foundation. The Foundation also reports that more than 180,000 Americans develop epilepsy each year. However, thousands more cases may be misdiagnosed as sleeping disorders, causing these figures to jump significantly. This correlation and diagnosis can help determine the correct type of medication to administer to regulate the symptoms, in turn saving hundreds of hours of lost time at work and millions of dollars.
Key Features
* Provides the first comprehensive source of information available on the correlation between epilepsy and sleep
* Outlines sleeping disorder symptoms which may in fact be caused by epilepsy
* Well illustrated, easy-to-read text
* An essential text for epileptologists, psychiatrists, physicians, and sleep disorder therapists
* Written by internationally recognized experts in the field

Industry Reviews

"This is perhaps one of the most comprehensive and systematic reviews ever written on the complex relationship between epileptic phenomena and sleep.The editors have succeeded in gathering together, some of the most renowned scientists worldwide in the fields of sleep disorders and epilepsy in order to have a multi-authored first edition...The book is very easy to read...this is a standard textbook providing not only elementary, but advanced knowledge too, in the fields of epilepsy and sleep. Even the basic neuroscientists and the experienced sleep neurophysiologist will find it a useful resource in many instances." -European Journal of Paediatric Neurology, Dimitrios I Zafeiriou, 1st Department of Pediatrics, Aristotle University of Thessaloniki, Greece (September 2004) "This book covers a difficult area in detail. There is much useful information and the writing is quite dense and terse. This is an excellent reference that addresses the issues rarely approached elsewhere... Experts in the field will find it a valuable reference source." -DOODY'S PUBLISHING REVIEWS (February 2002)

Contributorsp. XV
Prefacep. XVII
Relationship of Epilepsy and Sleep: Overview
Introductionp. 2
Effect of Sleep on Epilepsyp. 2
Effect of Sleep on Generalized Tonic--Clonic Seizuresp. 3
Primary Generalized Tonic--Clonic Epilepsyp. 4
Juvenile Myoclonic Epilepsyp. 4
Absence Epilepsyp. 4
Lennox--Gastaut Syndromep. 6
West Syndromep. 7
Temporal Lobe Epilepsyp. 8
Frontal Lobe Epilepsyp. 10
Benign Focal Epilepsy of Childhoodp. 11
Autosomal Dominant Nocturnal Frontal Lobe Epilepsyp. 11
Electrical Status Epilepticus of Sleepp. 12
Landau--Kleffner Syndromep. 12
Effect of Epilepsy on Sleepp. 12
Effect of Epilepsyp. 12
Effect of Seizuresp. 13
Microarchitecture of Sleep and Epilepsyp. 13
Effect of Antiepileptic Drugs on Sleepp. 14
Use of Sleep and Sleep Deprivation in the Evaluation of Epilepsyp. 15
Referencesp. 15
Electrophysiology of Sleep
Introductionp. 19
Oscillatory Nature of the Electroencephalogramp. 20
Brain Structures Involved in Sleep Oscillationsp. 21
Sleep Oscillationsp. 23
Spindlesp. 23
Delta Oscillationsp. 25
Slow Cortical Oscillations and Delta Wavesp. 28
Interactions between Sleep Oscillations in Intact Brainsp. 32
How Do Sleep Oscillations Develop into Spike--Wave Seizures?p. 35
Referencesp. 37
Physiology Underlying Relationship of Epilepsy and Sleep
Introductionp. 43
Methods and Resultsp. 44
Penicillin Epilepsyp. 44
Amygdala Kindlingp. 45
Discussionp. 51
Primary Generalized Epilepsyp. 57
Localization-Related Epilepsiesp. 58
Conclusionsp. 58
Referencesp. 59
Sleep Deprivation and Epilepsy
Introductionp. 63
Effect of Sleep on Epileptiform Dischargesp. 64
Activating Effect of Sleep Deprivation on Epileptiform Discharges on the Electroencephalogramp. 67
Effect of Sleep Deprivation on Seizuresp. 70
Effect of Seizures on Nocturnal Sleep and Daytime Functionp. 71
Experimental Datap. 72
Summaryp. 72
Referencesp. 72
Generalized Epilepsy and Sleep
Introductionp. 75
Relations of Epileptic Seizures to Sleep--Wake Cyclep. 76
Sleep Pattern of Patients with Generalized Epilepsyp. 77
Relation of Epileptiform Discharges to the Sleep--Wake Cycle and Sleep Stages in Generalized Epilepsyp. 78
Sleep Deprivationp. 79
Effects of Antiepileptic Drugs on Sleepp. 79
Summaryp. 81
Referencesp. 81
Focal Epilepsy and Sleep
Introductionp. 85
Video Electroencephalography Polysomnographyp. 86
Interictal Spiking during Sleepp. 87
Modification of Sleep Architecture in Epilepsyp. 90
Nocturnal Seizures and Epilepsyp. 91
Effect of Antiepileptic Drugs on Sleepp. 96
Conclusionsp. 97
Referencesp. 98
Epilepsy in the Neonate and Infant and Sleep
Introductionp. 102
Unique Aspects of the Ultradian Sleep Rhythm of the Fetus and Neonatep. 103
Sleep Reorganization during Infancyp. 107
Epileptic Syndromes during Neonatal/Infancy Periodsp. 108
Neonatal Seizuresp. 108
Benign Familial Neonatal (Infantile) Convulsionsp. 109
Benign Epilepsies of Infancyp. 109
Early Infantile Epileptic Encephalopathyp. 112
Infantile Spasms or West Syndromep. 112
Severe Epileptic Encephalopathiesp. 114
Nonepileptic Behaviors during Sleepp. 114
Summaryp. 118
Referencesp. 118
Cyclic Alternating Pattern and Sleep
Epilepsy and Vigilance Statesp. 122
Sleep Propensity and Body Temperature Rhythmsp. 123
Sleep Intensity and Slow-Wave Sleepp. 124
Nonrapid Eye Movement/Rapid Eye Movement Sleep Cyclep. 125
Dynamics of Thalamic Neurons during Sleepp. 126
Low-Frequency ([1 Hz) Oscillations in the Human Sleep Electroencephalogramp. 127
Cyclic Alternating Pattern as a Marker of Sleep Instabilityp. 128
Scoring of Cyclic Alternating Pattern Parametersp. 129
Cyclic Alternating Pattern and Noncyclic Alternating Patternp. 129
Cyclic Alternating Pattern Ratep. 131
Effects of Cyclic Alternating Pattern on Epileptic Eventsp. 132
Primary Generalized Epilepsyp. 133
Lesional Epilepsy with Frontotemporal Focusp. 136
Benign Epilepsy with Rolandic Spikesp. 136
Arousal Mechanisms and Location of Interictal Focip. 139
Modulatory Effects of Phase A Subtypesp. 139
Cyclic Alternating Pattern and Nocturnal Motor Seizuresp. 141
Neurophysiological Bases of Electroencephalographic Synchronyp. 144
Comprehensive Overviewp. 145
Circadianp. 145
Homeostaticp. 146
Ultradianp. 146
Microstructuralp. 147
Conclusionsp. 148
Referencesp. 149
Electrical Status Epilepticus of Sleep
Introductionp. 156
Clinical and Neurophysiological Featuresp. 157
Clinical Findingsp. 157
Neuropsychological Deteriorationp. 159
Motor Impairmentp. 159
Electroencephalographic Findingsp. 160
Pathophysiologyp. 162
Differential Diagnosisp. 164
Landau--Kleffner Syndromep. 164
Lennox--Gastaut Syndromep. 164
Benign Epilepsy of Childhood with Centrotemporal Spikesp. 164
Atypical Benign Partial Epilepsyp. 165
Long-Term Evolution and Prognosisp. 165
Treatmentp. 166
Conclusionsp. 167
Referencesp. 168
Acquired Epileptic Aphasia
Introductionp. 174
Definitionp. 174
Epidemiologyp. 175
Clinical Featuresp. 175
Neurophysiological Characteristicsp. 177
Pathophysiologyp. 182
Evolution and Prognosisp. 183
Treatmentp. 183
Current Problemsp. 184
Referencesp. 186
Sleep Disorders in Epilepsy
Introductionp. 191
Primary Sleep Disorders in Patients with Epilepsyp. 192
Sleep Complaints and Sleep Hygienep. 194
Effects of Seizures on Sleep and Vigilancep. 195
Antiepileptic Drug Effects on Sleep and Vigilancep. 196
Predictors of Sleepiness in Epilepsyp. 198
Referencesp. 199
Non-Rapid Eye Movement Parasomnias
Introductionp. 204
Arousal Disordersp. 205
Sleepwalkingp. 206
Sleep Terrorsp. 206
Confusional Arousalsp. 207
Biological Basisp. 207
Differential Diagnosisp. 208
Diagnostic Evaluationp. 208
Managementp. 210
Sleep-Wake Transition Disordersp. 210
Sleep Startsp. 210
Sleep Talkingp. 210
Rhythmic Movement Disorderp. 211
Nocturnal Leg Crampsp. 212
Other Parasomniasp. 213
Sleep Enuresisp. 213
Nocturnal Dissociative Disorderp. 214
Sleep Bruxismp. 215
Sudden Unexplained Nocturnal Deathp. 216
Referencesp. 217
Rapid Eye Movement Sleep Behavior Disorder
Introductionp. 222
Animal Model of Rapid Eye Movement Sleep Behavior Disorder: Paradox Lostp. 222
Clinical Features of Rapid Eye Movement Sleep Behavior Disorderp. 225
Rapid Eye Movement Sleep Behavior Disorder: Diagnostic Methodsp. 229
Minimum Diagnostic Criteria of Rapid Eye Movement Sleep Behavior Disorderp. 230
Treatment of Rapid Eye Movement Sleep Behavior Disorderp. 230
Differential Diagnosis of Rapid Eye Movement Sleep Behavior Disorderp. 231
Associated Findings in Rapid Eye Movement Sleep Behavior Disorderp. 231
Association with Parkinsonism and Other Extrapyramidal Disordersp. 231
Association with Narcolepsyp. 235
Parasomnia Overlap Disorderp. 236
Association of Rapid Eye Movement Sleep Behavior Disorder with Specific Human Leukocyte Antigen Haplotypesp. 236
Conclusionp. 237
Referencesp. 237
Nocturnal Paroxysmal Dystonia and Frontal Lobe Epilepsy
Nocturnal Paroxysmal Motor Phenomenap. 241
Episodic Nocturnal Wanderingsp. 242
Diurnal Paroxysmal Dyskinesias Responsive to Anticonvulsantsp. 242
Hypogenic Paroxysmal Dystonia or Epilepsy?p. 243
Other Sleep-Related Paroxysmal Eventsp. 243
Nocturnal Frontal Lobe Epilepsyp. 244
Autosomal Dominant Frontal Lobe Epilepsyp. 245
Summaryp. 246
Referencesp. 247
Introductionp. 251
Clinical Featuresp. 253
Triggering Factorsp. 254
Distribution of the Muscle Weaknessp. 255
Abruptness of the Attackp. 255
Reflexes during the Attackp. 255
Associated Symptomsp. 256
Pathophysiology of Cataplexyp. 256
Pharmacological Manipulations in Cataplexyp. 257
Conclusionp. 260
Referencesp. 260
Video Electroencephalography Polysomnography
Introductionp. 264
Epilepsyp. 264
Benign Focal Epilepsy of Childhoodp. 264
Frontal Lobe Epilepsyp. 265
Generalized Epilepsyp. 265
Parasomniap. 266
Confusional Arousalp. 266
Sleepwalkingp. 266
Sleep Terrorsp. 267
Rapid Eye Movement Behavior Disorderp. 267
Psychogenic Seizuresp. 267
Video Electroencephalography--Polysomnographyp. 267
Technical Aspectsp. 269
Electroencephalographyp. 269
Electrooculographyp. 270
Electromyographyp. 270
Electrocardiographyp. 271
Respirationp. 271
Case Examplesp. 272
p. 272
p. 275
p. 279
Summaryp. 283
Referencesp. 283
Postictal State
Introductionp. 286
Postictal Delirium/Psychosisp. 286
Postictal Lethargy/Confusionp. 287
Postictal Sleepp. 288
Postictal Coma/Encephalopathyp. 290
Referencesp. 291
Indexp. 293
Table of Contents provided by Syndetics. All Rights Reserved.

ISBN: 9780122167706
ISBN-10: 0122167708
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 300
Published: 1st December 2000
Country of Publication: US
Dimensions (cm): 22.91 x 15.19  x 1.91
Weight (kg): 0.59