| Aldehyde Dehydrogenase | |
| Aldelhyde Dehydrogenases - The 1992 Perspective | p. 1 |
| Metabolic Role of Aldehyde Dehydrogenase | p. 5 |
| Effects of Aldehyde Products of Lipid Peroxidation on the Activity of Aldehyde Metabolizing Enzymes in Hepatomas | p. 17 |
| Metabolic Interactions of 4-Hydroxynoenal, Acetaldehyde and Glutahione in Isolated Liver Mitochondria | p. 27 |
| Biological Role of Human Cytosolic Aldehyde Dehyrogenase 1: Hormonal Response, Retinal Oxidation and Implication in Testicular Feminization | p. 37 |
| Human Cytosolic Aldehyde Dehydrogenase in Androgen Insensitivity Syndrome | p. 45 |
| The Use of Immortalized Mouse L1210/OAP Cells Established in Culture to Study The Major Class 1 Aldehyde Dehydrogenase-Catalyzed Oxidation of Aldehydes in Intact Cells | p. 51 |
| Enhanced Transcription of the Cytosolic ALDH Gene in Cyclophosphamide Resistant Human Carcinoma Cells | p. 63 |
| Attempts to Increase the Expression of Rat Liver Mitochondrial Aldehye Dehydrogenase in E. coli by Altering the mRNA | p. 73 |
| Preliminary Characterization of the Rat Class 3 Aldehyde Dehydrogenase Gene | p. 81 |
| Human High-K[subscript m] Aldehyde Dehydrogenase (ALDH3): Molecular, Kinetic, and Structural Features | p. 87 |
| Overexpression or Polycyclic Aromatic Hydrocarbon-Mediated Induction of an Apparently Novel Class 3 Aldehyde Dehydrogenase in Human Breast Adenocarcinoma Cells and Its Relationship to Oxazaphosphorine-Specific Acquired Resistance | p. 99 |
| Tumor-Associated Aldehyde Dehydrogenase (ALDH3): Expression in Different Human Tumor Cell Lines with and without Treatment with 3-Methylcholanthrene | p. 115 |
| Sexual Differentiation in the Induction of the Class 3 Aldehyde Dehydrogenase | p. 123 |
| Mouse Class 3 Aldehyde Dehydrogenases: Positive and Negative Regulation of Gene Expression | p. 131 |
| Human Stomach Aldehyde Dehydrogenase, ALDH[Subscript 3] | p. 141 |
| Bovine Corneal Aldehyde Dehydrogenases: Evidence for Multiple Gene Products (ALDH3 and ALDHX) | p. 153 |
| Carbonyl-Metabolizing Enzymes and Their Relatives Recruited as Structural Proteins in the Eye Lens | p. 159 |
| Members of the ALDH Gene Family are Lens and Corneal Crystallins | p. 169 |
| Retinoic Acid Synthesis in the Developing Retina | p. 181 |
| Human Liver High Km Aldehyde Dehydrogenase (ALDH4): Properties and Structural Relationship to the Yeast Glutamic [gamma]-Semialdhyde Dehydrogenase | p. 191 |
| Effect of Some Compounds Related to Disulfiram on Mitochondrial Aldehyde Dehydrogenase in Vitro and in Vivo | p. 199 |
| Photoaffinity Labeling of Aldehyde Dehydrogenase from Horse Liver by P[superscript 1]-N[superscript 6]- (4-Azidophenylethyl) Adenosine-P[superscript 2][4-(3-Azidopyridinio)Butyl] Diphosphate | p. 211 |
| Aldehyde Dehydrogenase: Aldehyde Dehydrogenation and Ester Hydrolysis | p. 221 |
| Is the Single Site Binding Model for Aldehyde Dehydrogenase an Oversimplification? The One-Site, Two-Site Debate Revisited | p. 233 |
| Crystallization and Preliminary X-Ray Analysis of Bovine Mitochondrial Aldehyde Dehydrogenase and Human Glutathione-Dependent Formaldehyde Dehydrogenase | p. 245 |
| Aldose Reductase | |
| Aldo-Keto Reductases: An Overview | p. 251 |
| Location of an Essential Arginne Residue in the Primary Structure of Pig Aldose Reductase | p. 259 |
| Cys[superscript 298] Is Responsible for Reversible Thiol-Induced Variation in Aldose Reductase Activity | p. 267 |
| Substrate Specificity of Reduced and Oxidized Forms of Human Aldose Reductase | p. 279 |
| Kinetic Alteration of Human Aldose Reductase by Mutagenesis of Cysteine Residues | p. 289 |
| Inhibition of Aldose Reductase by (2,6-Dimethylphenylsulphonyl) Nitromethane: Possible Implications for the Nature of an Inhibitor Binding Site and a Cause of Biphasic Kinetics | p. 301 |
| Sepiapterin Reductase and ALR2 ("Aldose Reductase") from Bovine Brain | p. 313 |
| Polymorphisms of the Aldose Reductase Locus (ALR2) and Suseptibility to Diabetic Microvascular Complications | p. 325 |
| Carbonyl Reductase | |
| Polycyclic Aromatic Hydrocarbons and Phenolic Antioxidants do not Significantly Induce Carbonyl Reductase in Human Cell Lines | p. 333 |
| The Purification and Properties of a Novel Carbonyl Reducing Enzyme from Mouse Liver Microsomes | p. 339 |
| Properties and Stereoselectivity of Carbonyl Reductases Involved in the Ketone Reduction of Warfarin and Analogues | p. 351 |
| Activation of Pulmonary Carbonyl Reductase by Aromatic Amines and Pyridine Ring-Containing Compounds | p. 361 |
| Unique Dihydrodiol Specific Dehydrogenase of Bovine Liver: Inhibition Studies and Comparison with Aldo/Keto Reductase | p. 371 |
| Carbonyl Reduction by 3[alpha]-HSD from Comamonas testosteroni - New Properties and Its Relationship to the Scad Family | p. 379 |
| Alcohol Dehydrogenase | |
| Substrate Specificity of Alchohol Dehydrogenases | p. 391 |
| The Influence of pH on the Substrate Specificity and Stereoselectivity of Alcohol Dehydrogenase from Horse Liver | p. 401 |
| The Catalytic Specificity of Liver Alcohol Dehydrogenase: Vitamin A Alcohol and Vitamin A Aldehyde Activities | p. 411 |
| A Synthetic Approach to Analysis of the Structural Zinc Site of Alcohol Dehydrogenase | p. 419 |
| Kinetics of a Glycine for Arg-47 Human Alcohol Dehydrogenase Mutant can be Explained by Lys-228 Recruitment into the Pyrophosphate Binding Site | p. 429 |
| Site-Directed Mutagenesis of Mammalian Alcohol and Sorbitol Dehydrogenases Map Functional Differences within the Enzyme Family | p. 439 |
| Horse Liver Alcohol Dehydrogenase-S-Isozyme: Confirmation of the Primary Structure by Protein Sequencing and Ion Spray Mass Spectrometry | p. 451 |
| Mixed Substrate Experiments with Class III (chi) Alcohol Dehydrogenases from Human and Pig Liver and Stomach | p. 457 |
| Glutathione-Dependent Formaldehyde Dehydrogenase/ClassIII Alcohol Dehydrogenase: Further Characterization of the Rat Liver Enzyme | p. 465 |
| Class IV Alcohol Dehydrogenase: Structure and Function | p. 475 |
| The Oxidation of Aldehydes by Horse Liver Alcohol Dehydrogenase | p. 481 |
| Effect of Glycation Upon Activity of Liver Alcohol Dehydrogenase | p. 493 |
| Kinetically Specific Spin-Label Substrates of Liver Alcohol Dehydrogenase and of Liver Aldehyde Dehydrogenase | p. 501 |
| Fluorescence Studies of Tenary Complexes of Liver Alcohol Dehydrogenase | p. 513 |
| Evolutionary Relationships of Branched Chain and Non-Specific Alcohol and Aldehyde Dehydrogenases | p. 523 |
| Enzyme and Isozyme Developments within the Medium-Chain Alcohol Dehydrogenase Family | p. 533 |
| Tissue Distribution of Alcohol and Sorbitol Dehydrogenase mRNAs | p. 545 |
| The Role of Alcohol and Aldehyde Dehydrogenases in Alcohol-Related Diseases: Clinical Studies of Molecular Markers | p. 555 |
| Regulation of the Human Alcohol Dehydrogenase Genes ADH1, ADH2, and ADH3: Differences in cis-Acting Sequences at CTF/NF-1 Sites | p. 561 |
| DNA Elements Mediating Retinoid and Thyroid Hormone Regulation of Alcohol Dehydrogenase Gene Expression | p. 571 |
| Modulation of Hepatic and Renal Alcohol Dehydrogenase Activity and mRNA by Steroid Hormones in Vivo | p. 581 |
| Alcohol- and Aldehyde-Dehydrogenase: Modulation by Biogenic Amine Metabolites, Neuropeptides and Psychoactive Agents | p. 591 |
| Microbial Alcohol, Aldehyde, and Formate Ester Oxidoreductases | p. 605 |
| Carbonyl Metabolising Enzymes in Alkane-Grown Microorganisms | p. 621 |
| Index | p. 631 |
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