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Enzyme Kinetics : From Diastase to Multi-enzyme Systems - Arthur R. Schulz

Enzyme Kinetics

From Diastase to Multi-enzyme Systems

Paperback Published: 27th March 1995
ISBN: 9780521449502
Number Of Pages: 260

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This textbook for advanced courses in enzyme chemistry and enzyme kinetics covers the field of steady-state enzyme kinetics from the basic principles inherent in the Henri equation to the expressions that describe the control of multi-enzyme pathways. Steady-state kinetic equations are derived with the use of the connection matrix method, and an algorithm is developed that can be implemented easily for computer-based derivation of the equations. Throughout the book emphasis is placed on a proper interpretation of the kinetic behavior of multi-reactant enzymic reactions and on the interpretation of control coefficients in terms of metabolic control. Problems are included at the end of each chapter and their solutions are found at the end of the book.

"Currently, very few introductions to enzyme kinetics are available; this book could serve either as a text for a course in enqyme kinetics or as a reference for those needing an introduction to steady state enzyme kinetics. Definitely recommended." L.M. Prescott, Choice

Basic Steady State Enzyme Kinetics
Derivation of a rate equation
A closer look at the basic assumptions
Enzyme inhibition
Reversible enzyme-catalyzed reactions
Enzyme Reaction Sequence
Multi-reactant enzymic reactions
Analysis of multi-reactant enzyme kinetics
Prediction of reaction sequence
Enzyme-catalyzed isotopic exchange
Kinetic isotope effect on steady state parameters
The effect of pH on enzyme kinetics
Non-Hyperbolic Enzyme Kinetics
The causes of non-hyperbolic enzyme kinetics
Analysis of non-hyperbolic enzyme kinetics
The effect of subunit interactions on enzyme kinetics
Control of Multi-Enzyme Systems
Control of linear multi-enzyme systems
Control of branched multi-enzyme systems
Biochemical systems theory
Solutions To Problems
Author index
Subject index
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9780521449502
ISBN-10: 0521449502
Audience: Professional
Format: Paperback
Language: English
Number Of Pages: 260
Published: 27th March 1995
Publisher: Cambridge University Press
Country of Publication: GB
Dimensions (cm): 22.8 x 15.2  x 1.5
Weight (kg): 0.37

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