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Eicosanoids and other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 3 : Advances in Experimental Medicine and Biology - K.V. Honn

Eicosanoids and other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 3

Advances in Experimental Medicine and Biology

By: K.V. Honn (Editor), Lawrence J. Marnett (Editor), Santosh K. Nigam (Editor), Robert L. Jones (Editor), Patrick Y-.K. Wong (Editor)

Hardcover Published: 30th September 1997
ISBN: 9780306454875
Number Of Pages: 599

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This volume constitutes, in part, the proceedings of the Hong Kong Conference on "Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury" held in Hong Kong in October 1995. It contains papers by the symposium speakers, as well as poster contributions from researchers in this field. Since the discovery of "PROSTAGLANDIN-LIKE' substances 60 years ago. much has been learned. EICOSANOID is the new term that is used to include prostaglandins. thromboxanes, leukotrienes, lipoxins, isoprostanes, depoxilins, hydroxy acids, epoxy and hydroperoxy fatty acids. The conference focussed on recent development in underatanding the role of EICOSANOIDS in inflammation, cancer, and radiation damage. At the confer- ence, we also highlighted advances in newly developing areas such as "NO," "A POP- TOSIS and "ANANDAMIDE." The discovery of the structures of genes that encode several key enzymes and receptors of the Eicosanoid cascade, has allowed us to include reports in the "Alteration of the Gene Expression" section that reflects the most recent de- velopments in regulation for PGH-synthase and lipoxygenases. The editors are convinced that this volume will be an up-to-date and useful reference for investigators in both basic and clinical research.

Lipoxygenase: Studies on the Active Site of Leuktriene A4 Hydrolase
PGH Synthase: Disruption of the Mouse Cyclooxygenase I Gene: Characteristics of the Mutant and Areas of Future Study
Alteration of Gene Expression: Characterization of Prostaglandin H Synthase-2 Deficient Mice and Implications for Mechanisms of NSAID Action
Receptors: Structure and Regulation of Platelet Activating Factor Receptor Gene
Inflammation: PGE2 Regulation of B Lymphocytes and T Helper 1 and T Helper 2 Cells: Induction of Inflammatory Versus Allergic Response
Signal Transduction: Plasma Membrane Guanylate Cyclase: A Multimodule Transduction System
Anandamide: Anandamide Amidohydrolase from Porcine Brain: Partial Purification and Characterization
PAF: Cloning and Characterization of a Murine Platelet-Activating Factor Receptor Gene
Cell Growth and Apoptosis
Clinical Studies
Poster Sessions
76 Additional Articles
Index
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9780306454875
ISBN-10: 0306454874
Series: Advances in Experimental Medicine and Biology
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 599
Published: 30th September 1997
Publisher: Springer Science+Business Media
Country of Publication: US
Dimensions (cm): 25.4 x 17.8  x 3.81
Weight (kg): 3.06
Edition Number: 3