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Drugs : Photochemistry and Photostability :  Photochemistry and Photostability - Angelo Albini

Drugs : Photochemistry and Photostability

Photochemistry and Photostability

By: Angelo Albini (Editor), E. Fasani (Editor)

Hardcover

Published: October 1998
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Since Pasteur in 1846, scientists have known that many drugs are photoreactive, but until recently research into this was limited. This text presents the basic elements of this science and serves as an excellent introduction to photochemistry.

Photochemistry of Drugs: An Overview and Practical Problemsp. 1
Medicinal Photochemistry (An Introduction with Attention to Kinetic Aspects)p. 74
Photoreactivity of Selected Antimalarial Compounds in Solution and in the Solid Statep. 87
Photochemistry of Diuretic Drugs in Solutionp. 100
New Results in the Photoinstability of Antimycoticsp. 116
Photoreactivity versus Activity of a Selected Class of Phenothiazines: A Comparative Studyp. 134
Photoprocesses in Photosensitising Drugs Containing a Benzophenone-like Chromophorep. 150
Photostability of Coumarinp. 162
Photostabilities of Several Chemical Compounds used as Active Ingredients in Sunscreensp. 171
An Analytical and Structural Study of the Photostability of some Leukotriene B4 Antagonistsp. 182
Molecular Mechanisms of Photosensitization Induced by Drugs on Biological Systems and Design of Photoprotective Systemsp. 194
A Comparison between the Photochemical and Photosensitising Properties of Different Drugsp. 211
Photostability of Drug Substances and Drug Products: A Validated Reference Method for Implementing the ICH Photostability Study Guidelinesp. 227
The Elaboration and Application of the ICH Guideline on Photostability: A European Viewp. 243
Selecting the Right Source for Pharmaceutical Photostability Testingp. 247
Design and Validation Characteristics of Environmental Chambers for Photostability Testingp. 272
Design Limits and Qualification Issues for Room-size Solar Simulators in a GLP Environmentp. 288
Actinometry: Concepts and Experimentsp. 295
trans-2-Nitrocinnamaldehyde as Chemical Actinometer for the UV-A Range in Photostability Testing of Pharmaceuticalsp. 305
Subject Indexp. 317
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9780854047437
ISBN-10: 0854047433
Series: Special Publication (Royal Society of Chemistry) : Book 225
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 334
Published: October 1998
Publisher: Royal Society Of Chemistry
Country of Publication: GB
Dimensions (cm): 23.4 x 15.6  x 2.54
Weight (kg): 0.77