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DNA Repair and Replication contains an up-to-date review of general principles of DNA replication and an overview of the multiple pathways involved in DNA repair. Specific DNA repair pathways, including base-excision repair, light-dependent direct reversal of UV-damage, nucleotide-excision repair, transcription-coupled repair, double-strand break repair, and mismatch repair, are each discussed in separate chapters.
Selected Contents:
-Base Excision Repair
-Eukaryotic DNA Mismatch Repair
-Double Strand Break Repair
-Functions of DNA Polymerases
-Somatic Hypermutation: A Mutational Panacea
| Base excision repair | |
| Nucleotide excision repair in E. coli and man | |
| Photolyase and cryptochrome blue-light photoreceptors | |
| Coordination of repair, checkpoint, and cell death responses to DNA damage | |
| Functions of DNA polymerases | |
| Cellular functions of DNA polymerase [zeta] and Rev1 protein | |
| DNA polymerases [eta] and [iota] | |
| Properties and functions of Escherichia coli : pol IV and pol V | |
| Mammalian pol [kappa] : regulation of its expression and lesion substrates | |
| DNA postreplication repair modulated by ubiquitination and sumoylation | |
| Somatic hypermutation : a mutational panacea | |
| Table of Contents provided by Blackwell. All Rights Reserved. |
ISBN: 9780120342693
ISBN-10: 0120342693
Series: Advances in Protein Chemistry : Book 69
Audience:
Professional
Format:
Hardcover
Language:
English
Number Of Pages: 368
Published: 9th December 2004
Publisher: Elsevier Science Publishing Co Inc
Country of Publication: US
Dimensions (cm): 22.9 x 15.2
x 2.54
Weight (kg): 0.77
