The binding of proteins to DNA and the manipulation of DNA by proteins are crucial aspects of the biological role of DNA in the living cell. This book provides a comprehensive and lucid discussion of the molecular interactions involved.
The value of this analysis is found in the insight it provides into the mechanism of complex systems.... the text is generally well-written and flows smoothly. [this work] is full of insights and stimulating in its unification of structure and function, a perspective that is increasingly inmportant in molecular biology. Trends in Genetics; Andrew Travers has done an excellent job of selecting examples illustrating the central theme of the book...the figures are instructive, well designed and selected...I wholeheartedly recommend this book for all structural and molecular biologists who are interested in the biological role of DNA - Trends in Biochemical Sciences; ...the book does bring together areas in a juxtaposition unique to its author...explained with the authority one would expect from Travers. - Nature; ...the book quickly takes us beyond the straightforward undergraduate texts, to provide a helpful source of information and discussion material for advanced undergraduate or Masters'courses. Journal of Biological Education; The value of this analysis is found in the insight it provides into the mechanism of complex systems.... the text is generally well-written and flows smoothly. [this work] is full of insights and stimulating in its unification of structure and function, a perspective that is increasingly r portant in molecular biology. Trends in Genetics; Overall, this is a densely detailed text and worth its place on the shelf of practitioners in the field who wish to maintain an overall view...gathers together current knowledge in a useful way - Current Biology
DNA structure. DNA-protein interactions: the three-dimensional architecture of DNA-protein complexes. DNA-protein interactions: sequence specific recognition. The mechanism of RNA chain initiation. The regulation of promoter selectivity in eubacteria. The mechanism of eukaryotic transcription. Chromatin and transcription. Index.
Number Of Pages: 192
Published: September 2009
Publisher: SPRINGER VERLAG GMBH
Country of Publication: GB
Dimensions (cm): 23.39 x 15.6
Weight (kg): 0.28