Disorders of Voluntary Muscle

By: George Karpati, David Hilton-Jones (Editor), Kate Bushby (Editor), Robert C. Griggs (Editor)

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Hardcover | 21 January 2010 | Edition Number 8

At a Glance

Hardcover
536 Pages

Edition Type
Revised

Dimensions(cm)
22.9 x 28.3 x 3.5

Hardcover

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This major new edition fulfils the need for a single-volume, up-to-date information resource on the etiology, pathogenesis, diagnosis and treatment of diseases of skeletal muscles, including the muscular dystrophies, mitochondrial myopathies, metabolic myopathies, ion channel disorders, and dysimmune myopathies. As background to the clinical coverage, relevant information on advances in molecular and developmental biology, immunopathology, mitochondrial biology, ion-channel dynamics, cell membrane and signal transduction science, and imaging technology is summarized. Combining essential new knowledge with the fundamentals of history-taking and clinical examination, this extensively illustrated book will continue to be the mainstay for practising physicians and biomedical scientists concerned with muscle disease. Regular updates on the clinical and basic science aspects of muscle disease - written mainly by rising stars of myology - will be published on an accompanying website.

Industry Reviews

'After reading through the text, one will achieve a solid foundation in clinical myology. This book will be useful for any clinician who diagnoses and manages patients with muscle disease, and for students, residents, and fellows with an interest in such.' Mark B. Bromberg, MD, PhD, Neurology

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You Can Find This Book In

Non-Fiction Medicine Clinical & Internal Medicine Rheumatology Neurology & Clinical Neurophysiology Musculoskeletal Medicine

Preface
Foreword
The Scientific Basis of Muscle Disease
Structure and function of muscle fibres and motor units
Myogenic precursor cells
Biochemical and molecular basis of muscle disease
Investigation of Muscle Disease
Electromyography and related techniques
Histopathology and immunoanalysis of muscle
Ultrastructural study of muscle
Diagnostic imaging of muscle
Description of Muscle Disease
General Aspects:
The clinical assessment and a guide to classification of the myopathies
The principles of molecular therapies for muscle diseases
Specific Diseases:
Dystrophinopathies
Muscular dystrophies presenting with proximal muscle weakness
Dystrophies and myopathies of early childhood onset
Congenital myopathies
Muscle diseases with prominent muscle contractures
Facioscapulohumeral muscular dystrophy
Distal myopathies
Oculopharyngeal muscular dystrophy
Myotonic dystrophy
Mitochondrial myopathies and related disorders
Metabolic myopathies
Muscle ion channelopathies and related disorders
Inflammatory and dysimmune myopathies
Myasthenia gravis and myasthenic syndromes [autoimmune and genetic]
Endocrine and toxic myopathies
Myofibrillar myopathy
Hereditary inclusion body myopathies
Other myopathies
Table of Contents provided by Publisher. All Rights Reserved.

Disorders of Voluntary Muscle

At a Glance

Hardcover

Industry Reviews

Shipping

How to return your order

Defective items

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