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Dialysing for Life : The Development of the Artificial Kidney : Development of the Artificial Kidney - J. van Noordwijk

Dialysing for Life : The Development of the Artificial Kidney

Development of the Artificial Kidney

By: J. van Noordwijk (Editor)

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Seeing a patient die under his hands because there is no adequate treatment causes an emotion and a frustration in a doctor, which sometimes stimulates him to try to develop a new type of treatment. Seeing so many wounded young soldiers die due to renal failure in World War I incited the German doctor Georg Haas to try to develop an artificial kidney. He had to give up in despair in 1928. Ten years later doctor Willem Kolff saw a young man die in his ward in the University Hospital of Groningen due to renal failure. By that time two essential factors for an artificial kidney had become available: a drug to keep the blood from clotting outside of the body and an efficient dialysing membrane through which waste substances can pass from the blood into the dialysing fluid. Kolff succeeded in creating the rotating artificial kidney which he started using in the town hospital of Kampen in 1943. The rotation of this artificial kidney started a revolution that made it possible for thousands of kidney patients all over the world to keep on living - and sometimes to forget their disease for the time being. In addition it gave rise to the development of other artificial organs such as the heart-lung machine, the artificial heart and the artificial eye. Doctor Jacob van Noordwijk, the author of this book, was Kolff's first assistant in the treatment of the first 15 patients. How Kolff succeeded in spite of all the limitations imposed by the German occupation of the Netherlands and in spite of the absence of antibiotics and other medical tools which are common nowadays makes a story which may sound incredible. Yet it did happen and visitors to the town of Kampen can still see the hospital building where it all took place.

Prefacep. vii
Acknowledgementp. ix
Introductionp. xi
The first dialysis in 1943p. 1
The prelude to the first dialysis in 1943p. 5
Why Dr Kolff wished to develop an artificial kidneyp. 5
The search for a serviceable artificial kidneyp. 7
The May days of 1940p. 11
To Kampen: the artificial kidney becomes a realityp. 14
Notesp. 17
Step by step towards a robust machinep. 19
Towards a continuous perfusionp. 19
The yield of the dialysisp. 20
Protection of erythrocytes during dialysisp. 22
In the meantime the war went onp. 23
All the things we did not havep. 25
The first series of 17 patientsp. 27
Notesp. 32
The second and third artificial kidneyp. 33
Technical developments in the apparatusp. 33
The first kidney goes to The Haguep. 34
The third kidney goes to Amsterdamp. 36
Notesp. 37
Hibernation of the kidney 1944-1945p. 39
Notesp. 43
Recognition at home and abroadp. 45
Notesp. 51
New ways of fighting uraemiap. 53
Peritoneal dialysisp. 53
Intestinal perfusionp. 54
Non-rotating artificial kidneysp. 55
Dietary reduction of protein breakdownp. 55
Notesp. 57
Breathing with a kidneyp. 59
The kidney in Canada and the USAp. 61
The artificial kidney in Montrealp. 61
The artificial kidney in London, Ontariop. 62
Sire of 'kidney' is Frankfurter: a leech also helpedp. 65
Furstration in Clevelandp. 69
The twin-coil kidney, suitable for mass productionp. 69
The artificial kidney in Bostonp. 73
The Department of Artificial Organs at the University of Utahp. 76
Notesp. 78
The place of the artificial kidney in present-day medicine--and how it was achievedp. 81
The accessibility of the patient's blood vessels for repeated dialysisp. 82
Home dialysisp. 84
Renal transplantationp. 87
The 1972 legal regulation for reimbursementp. 89
The technical evolution of the artificial kidneyp. 90
Does the clinician make an effective use of what is technically available?p. 93
Notesp. 94
Renal dialysis in the Netherlands and in Europep. 97
Renal dialysis in the Netherlandsp. 97
Renal dialysis in Europep. 99
Renal dialysis in the holidaysp. 100
Notesp. 103
On the shoulders of Kolffp. 105
Notesp. 107
Has Kolff reached his goal?p. 109
A new life for old dialysersp. 113
Table of Contents provided by Syndetics. All Rights Reserved.

ISBN: 9780792368403
ISBN-10: 0792368401
Series: Development of the Artificial Kidney
Audience: General
Format: Paperback
Language: English
Number Of Pages: 114
Publisher: Springer
Country of Publication: NL
Dimensions (cm): 23.39 x 15.6  x 0.74
Weight (kg): 0.2