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Diagnostic Electron Microscopy : A Text-Atlas :  A Text-Atlas - Richard G. Dickersin

Diagnostic Electron Microscopy : A Text-Atlas

A Text-Atlas

Hardcover

Published: 2000
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This text atlas, now in its second edition, presents in simplest form the basic diagnostic criteria used by the electron microscopist in studying neoplasms and other diseases encountered in the routine practice of pathology. Every field of electron microscopy is covered and low magnification plates are juxtaposed with higher magnifications to illustrate diagnostic features. The largest section of the book is devoted to neoplasms as this is the area in which most diagnostic problems occur. Renal glomerular disease is another important category in which ultrastructural study may be critical in diagnosis; infectious diseases, especially those of viral, protozoan, and unusual bacterial etiologies, are a third area in which electron microscopy may be used to establish or susbstantiate a diagnosis. All of these areas are comprehensively covered with concise, readable text and more than 800 first-quality images. This book is the preeminent reference for pathologists needing current information on the role of ultrastructure in diagnostic pathology.

Prefacep. vii
Acknowledgmentsp. ix
Contributorsp. xix
Normal Cell Ultrastructure and Functionp. 1
Cytoplasmic Organellesp. 1
Cytoskeleton (Cytoplasmic Matrix Structures)p. 4
Cytoplasmic Inclusionsp. 4
Nuclear Organellesp. 4
Organization of Organelles Within the Cellp. 5
Cell Attachment Sitesp. 5
Selective Embryologyp. 7
Embryogenesis from Fertilization Through Three Weeksp. 7
Differentiation of the Paraxial Mesodermp. 9
Differentiation of the Intermediate Mesodermp. 10
Differentiation of the Lateral Mesodermp. 11
Comparison of Embryonic Mesodermal Differentiation with Embryonal Rhabdomyosarcoma, Wilms'Tumor, and Mesotheliomap. 11
Large Cell Neoplasmsp. 27
Carcinomap. 27
Adenocarcinoma (and Adenoma)p. 27
Squamous Cell Carcinomap. 65
Transitional Cell (Urothelial) Carcinomap. 65
Undifferentiated Carcinomap. 88
Melanomap. 88
Mesotheliomap. 88
Lymphomap. 89
Histiocytic Disordersp. 116
Macrophagic Lesionsp. 116
Dendritic Cell Lesionsp. 117
Mastocytosis and Mastocytomap. 124
Small Cell Neoplasmsp. 147
Neuroendocrine Carcinomap. 147
Neuroblastomap. 147
Ewing's Sarcomap. 161
Primitive Neuroectodermal Tumorp. 161
Embryonal and Alveolar Rhabdomyosarcomap. 169
Rhabdoid Tumorp. 169
Nephroblastoma (Wilms'Tumor)p. 169
Lymphoma (Small Cell)p. 197
Plasmacytomap. 197
Desmoplastic Small Round Cell Tumor with Divergent Differentiationp. 197
Small Cell Osteosarcomap. 197
Mesenchymal Chondrosarcomap. 209
Leukemiasp. 217
Myelocytic Leukemiap. 217
Monocytic and Myelomonocytic Leukemiap. 227
Lymphocytic Leukemiap. 227
Erythrocytic Leukemiap. 227
Megakaryocytic Leukemiap. 234
Hairy Cell Leukemia (Leukemic Reticuloendotheliosis)p. 234
Spindle Cell Neoplasms and Their Epithelioid Variantsp. 247
Fibrous Neoplasmsp. 247
Malignant Fibrous Histiocytomap. 264
Cartilaginous Neoplasmsp. 278
Osteoblastoma and Osteosarcomap. 278
Synovial Sarcomap. 295
Adipose Neoplasmsp. 295
Smooth Muscle Neoplasmsp. 320
Skeletal Muscle Neoplasmsp. 320
Vascular Neoplasmsp. 341
Hemangiopericytomap. 341
Schwannoma and Malignant Schwannomap. 359
Granular Cell Tumorp. 359
Neurofibromap. 369
Sarcomatoid (Spindle Cell) Carcinomap. 369
Sarcomatous Thymoma, Melanoma, and Mesotheliomap. 369
Gonadal and Related Neoplasmsp. 391
Surface Epithelial-Stromal Tumors of the Ovaryp. 391
Serous Tumorsp. 391
Mucinous Tumorsp. 406
Endometrioid Tumorsp. 406
Clear Cell Tumorsp. 418
Transitional Cell Tumors (Brenner and Non-Brenner Types)p. 424
Squamous Cell Tumors (Epidermoid Cyst and Squamous Cell Carcinoma)p. 424
Mixed Epithelial Tumorsp. 424
Undifferentiated Carcinomap. 424
Sex Cord-Stromal Tumorsp. 424
Granulosa Cell Tumorp. 424
Thecomap. 439
Fibromap. 439
Signet-Ring Stromal and Related Tumorsp. 439
Sertoli-Stromal Cell Tumors (Androblastomas)p. 439
Sex Cord Tumors with Annular Tubulesp. 451
Gynandroblastomap. 451
Sex Cord-Stromal Tumors Unclassifiedp. 451
Steroid (Lipid) Cell Tumorsp. 451
Germ Cell Tumorsp. 451
Dysgerminoma (Seminoma)p. 451
Yolk Sac Tumor (Endodermal Sinus Tumor)p. 462
Embryonal Carcinomap. 462
Choriocarcinoma and placental Site Tumor (and Normal placenta)p. 462
Teratoma (Immature and Mature; Monodermal)p. 462
Gonadoblastomap. 478
Adenomatoid Tumorp. 478
Tumors of Uncertain Origin and Miscellaneous Tumorsp. 478
Ovarian Small Cell Carcinoma, Hypercalcemia Typep. 478
Small Cell Carcinoma, Pulmonary Typep. 478
Tumor of Probable Wolffian Originp. 478
Central Nervous System Neoplasmsp. 488
Meningiomap. 488
Astrocytomap. 499
Oligodendrogliomap. 499
Ependymoma (and Subependymoma)p. 510
Choroid Plexus Neoplasmsp. 510
Neuronal and Mixed Neuronal Glial Neoplasms, Including Embryonal Formsp. 510
Gangliocytoma (Central Ganglioneuroma)p. 510
Ganglioneuroma (Peripheral)p. 510
Gangliogliomap. 526
Central Neurocytomap. 526
Neuroblastomap. 526
Ganglioneuroblastomap. 528
Ependymoblastomap. 528
Primitive Neuroectodermal Tumorp. 528
Medulloblastomap. 528
Germinoma (and Embryonal Carcinoma, Choriocarcinoma, and Teratoma)p. 528
Pineocytoma and Pineoblastomap. 532
Hemangiomap. 532
Hemangioblastomap. 532
Pituitary Adenomap. 543
Miscellaneous Neoplasmsp. 560
Neuroendocrine Neoplasmsp. 560
Carcinoid/Islet Cell Neoplasmsp. 560
Medullary (C-Cell) Carcinoma of the Thyroidp. 569
Parathyroid Carcinoma and Adenomap. 569
Paraganglioma (Chemodectoma), Extra-adrenalp. 569
Pheochromocytoma (Adrenal Paraganglioma)p. 569
Monomorphic Adenomap. 569
Pleomorphic Adenomap. 585
Adenoid Cystic Carcinomap. 585
Mucoepidermoid Carcinomap. 585
Alveolar Soft-part Sarcomap. 604
Chordomap. 604
Epithelioid Sarcomap. 613
Hepatoblastomap. 613
Embryonal Sarcoma of Liverp. 613
Gastrointestinal Stromal Tumorp. 613
Gastrointestinal Autonomic Nerve Tumor (plexosarcoma)p. 628
Pulmonary Blastomap. 628
Juxtaglomerular Cell Tumorp. 628
Infectious Agentsp. 648
Bacteriap. 648
Virusesp. 661
Protozoap. 680
Pneumocystis cariniip. 680
Toxoplasma gondiip. 680
Cryptosporidium parvump. 680
Trypanosoma cruzip. 694
Microsporida (M. enterocytozoon bieneusi and M. septata intestinale)p. 694
Giardia lambliap. 694
Fungip. 702
Histoplasma capsulatump. 702
Genetic and Metabolic Diseasesp. 710
Storage Diseasesp. 710
Erdheim-Chester Disease (Fibroxanthomatosis)p. 738
Porphyriap. 738
Alpha-1-Antitrypsin Deficiencyp. 738
Pulmonary Alveolar Proteinosisp. 738
Mitochondrial Abnormalitiesp. 747
Wilson's Diseasep. 747
Amyloidosisp. 747
Amiodarone Toxicityp. 757
Adriamycin Toxicityp. 757
Hemosiderosisp. 757
Cholestasisp. 757
""Melanosis"" (Lipofuscinosis) Coli and Prostaticusp. 757
Primary Ciliary Dyskinesiap. 771
Renal Glomerular Diseasep. 782
The Normal Glomerulusp. 782
Location of Electron-Dense Depositsp. 785
Diseases with Scant or No Glomerular Depositsp. 786
Minimal Change Disease (Lipoid Nephrosis)p. 786
IgM Nephropathyp. 787
Focal and Segmental Glomerulosclerosis (Primary and Secondary Types)p. 788
Focal Segmental Glomerulosclerosis, Collapsing Variant, Including HIV-Associated Nephropathy and Heroin Abuse Nephropathyp. 792
Congenital Nephrotic Syndromep. 794
Diabetic Nephropathyp. 797
Thin Glomerular Basement Membrane Disease (Benign Familial Hematuria)p. 800
Alport's Syndrome (Hereditary Nephritis)p. 803
Glomerular Diseases with Prominent Crescentsp. 806
Wegener's Granulomatosisp. 806
Anti-Glomerular Basement Membrane Nephritis (Goodpasture's Syndrome)p. 806
Diseases with Prominent Amorphous Dense Depositsp. 809
Postinfectious Glomerulonephritisp. 809
Membranous Glomerulonephritisp. 811
Membranoproliferative Glomerulonephritis, Type Ip. 815
IgA Nephropathy (Berger's Disease)p. 819
Henoch-Schönlein Purpurap. 819
Systemic Lupus Erythematosusp. 823
Tubuloreticular Inclusions and Tubular Confronting Cisternaep. 836
Diseases with Distinctive Ultrastructural Depositsp. 839
Dense-Deposit Disease (Membranoproliferative Glomerulonephritis, Type II)p. 839
Amyloidosisp. 843
Fibrillary Glomerulonephritisp. 846
Immunotactoid Glomerulopathyp. 851
Cryoglobulinemic Glomerulopathyp. 851
Systemic Light Chain Deposition Diseasep. 856
Monoclonal Gammopathyp. 856
Nail Patella Syndrome (Hereditary Osteo-onychodysplasia)p. 859
Collagen Type III Collagenofibrotic Glomerulopathyp. 859
Fabry's Diseasep. 863
Cystinosisp. 865
Glomerulopathy of Sickle Cell Disease/Traitp. 865
Diseases with Endothelial Reactionp. 868
Thrombotic Microangiopathy (in Hemolytic Uremic Syndrome, Thrombotic Thrombocytopenic Purpura, Scleroderma, Malignant Hypertension, Rejection, and Cyclosporine Toxicity)p. 868
Eclampsia/Preeclampsiap. 875
The Renal Allograftp. 877
Acute Allograft Glomerulopathyp. 877
Thrombotic Microangiopathy and the Renal Allograftp. 879
Acute Humoral Rejectionp. 879
Chronic Allograft Glomerulopathyp. 885
Other Lesions in Renal Transplantsp. 885
Diabetic Nephropathyp. 885
Membranous Glomerulonephritisp. 891
BK Virus (Polyomavirus)p. 891
Cyclosporine Nephropathyp. 891
Miscellaneous Lesionsp. 896
Microparticles in Depositsp. 896
Gentamicin Bodiesp. 896
Acute Tubular Injuryp. 899
Diseases of Skeletal Muscle and Peripheral Nervep. 912
Skeletal Musclep. 912
Muscular Dystrophy and Congenital Myopathyp. 920
Congenital Myopathiesp. 927
Metabolic Myopathiesp. 930
Mitochondrial Myopathiesp. 937
Inflammatory Myopathiesp. 937
Neurogenic Atrophyp. 949
Peripheral Nerve Diseasep. 951
Axonal Degeneration and Regenerationp. 953
Specific Peripheral Neuropathiesp. 963
Metabolic Neuropathies Associated with Diabetes Mellitusp. 966
Sensorimotor Neuropathies Associated with Hereditary Metabolic Diseasep. 966
Hereditary Neuropathiesp. 970
Amyloid Neuropathyp. 980
Immune-Mediated Neuropathiesp. 982
Infectious Neuropathiesp. 983
Neuropathy Associated with Paraneoplastic Syndromes and Dysproteinemiasp. 986
Indexp. 991
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9780387983882
ISBN-10: 0387983880
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 1005
Published: 2000
Publisher: SPRINGER VERLAG GMBH
Country of Publication: US
Dimensions (cm): 27.94 x 21.59  x 5.41
Weight (kg): 2.63
Edition Number: 2
Edition Type: Revised