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Diabetes : Clinical Science in Practice - R. D. G. Leslie

Diabetes

Clinical Science in Practice

By: R. D. G. Leslie (Editor), David C. Robbins (Editor)

Hardcover

Published: 31st March 1995
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This significant new publication provides a summary and overview of the most recent scientific advances in diabetes research, and highlights the role of these developments in advancing clinical practice. Diabetes is one of the major causes of morbidity and mortality in the developed world, and its prevalence elsewhere is on the increase. It affects in excess of 100 million people worldwide. Recent scientific advances have clarified our understanding of the causes and consequences of this devastating disease. These scientific developments are playing an increasingly important role in clinical practice and could well lead the way to the prevention of complications and even a cure for the disease. An international and authoritative team of authors draws together this knowledge and the most recent developments to provide an up-to-date account which will benefit researchers and clinicians.

'The editors, together with the eminent contributors, combine to make this an outstandingly informative book ... each specialist topic can stand alone as a review of the most recent research ... For anybody interested in diabetes it is an essential read.' D. M. Gasparro, British Journal of Biomedical Science 'In Diabetes: Clinical Science in Practice distinguished scientists provide an authoritative analysis of their subjects and assess the implications of recent advances.' Michael Edmonds, British Medical Journal 'The book is as up to date as a multiauthor textbook can hope to be ... It should fulfil the editors' intentions of increasing the scientific understanding of diabetes in their readers, in the hope of improving the care of diabetic patients.' Michael Edmonds, British Medical Journal ' ... as up to date as a multiauthor textbook can hope to be, containing many references to studies published in 1993 and 1994.' Michael Edmonds, British Medical Journal

The regulation of insulin gene transcription
Molecular structure of insulin
Regulation of insulin secretion
Insulin receptors
The role of protein phosphorylation in insulin action
Glucose transport mechanisms
Glucose homeostasis
Epidemiology of insulin-dependent diabetes mellitus (IDDM)
Genetics of IDDM
Aetiology of Type 1 (insulin-dependent) diabetes
Epidemiology of NIDDM
Genetic basis of the aetiology of non-insulin-dependent diabetes (NIDD)
Islet amyloid polypeptide and amyloid in the islets of Langerhans
Primary insulin resistance
Epidemiology of the complications of diabetes
Macrovascular disease in diabetes
Diabetic neuropathy
Diabetic foot infections
Ocular complications of diabetes
Diabetic nephropathy
The personal, social and economic burden of diabetic complications
Mortality among persons with diabetes
Glycation and diabetic complications
The sorbitol pathway and diabetic complications
Proteinuria and diabetic complications
Pharmacologic approaches to NIDDM
Insulin and insulin analogues
Hypoglycaemia
Strategies for prevention of Type 1 (insulin-dependent) diabetes
Treatment of early diabetic renal disease
Pancreatic transplantation in humans with diabetes mellitus
Rational insulin management of IDDM
Rationale in the management of non-insulin-dependent diabetes mellitus (NIDDM)
Psychosocial aspects of diabetes care
Index
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9780521450294
ISBN-10: 0521450292
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 508
Published: 31st March 1995
Publisher: Cambridge University Press
Country of Publication: GB
Dimensions (cm): 26.04 x 20.32  x 3.18
Weight (kg): 1.2