Delivery Systems for Peptide Drugs

Advanced Delivery Systems for Peptides and Proteins - Pharmaceutical Considerations.- Biotechnology and Protein Production.- Peptide Analysis: Critical Technology for Evaluating Delivery Approaches.- Bioreversible Derivatization of Peptides.- An Approach to Target Therapy. Synthesis and Biological Activity of Hydrophobic and Hydrophilic Enkephalin Analogues.- Temporal and Pharmacokinetic Aspect in Delivery of Peptides and Proteins.- Enzymatic Barriers to Peptide and Protein Absorption and the Use of Penetration Enhancers to Modify Absorption.- Intracellular Sorting of Proteins.- Biodegradable Polymers for Sustained Release of Polypeptides.- Controlled Delivery of Nafarelin, an Agonistic Analogue of LHRH, From Microspheres of Poly (D, L Lactic-Co-Glycolic) Acid.- The Oral Bioavailability of Peptides and Related Drugs.- Oral Delivery of Peptide Drugs.- Drug Delivery of Peptides: The Buccal Route.- Enhanced Absorption and Lymphatic Transport of Macromolecules via the Rectal Route.- Biopharmaceutical Aspects on the Intranasal Administration of Peptides.- Microspheres as a Potential Controlled Release Nasal Drug Delivery System.- NazlinR - Transnasal Systemic Delivery of Insulin.- Nasal Absorption of Enkephalins in Rats.- Intranasal Delivery of the Peptide, Salmon Calcitonin.- Metabolic Effects of Intranasally Administered Insulin and Glucagon in Man.- Human Calcitonin Administered by the Nasal Route: Bioavailability of Different Formulations and Efficacy in Post-Menopausal Osteoporosis.- Routes of Administration for Polar Compounds of Moderate Molecular Weight with Particular Reference to Analogues of Somatostatin.- The Transdermal Route for the Delivery of Peptides and Proteins.- Controlled-Release and Localized Targeting of Interferons.- Delivery of Macrophage Activating Factors by Means of Liposomes.- Activators of Plasminogen.- Biosynthetic Human Growth Hormone Identical to Authentic Material.- Delivery Systems for Recombinant Methionyl Human Growth Hormone.- Eledoisin and Ceruletide, Two Naturally Occurring Peptide Drugs of Nonmammalian Origin.- Consideration of the Proteins and Peptides Produced by New Technology for use as Therapeutics.- Key Issues in the Delivery of Peptides and Proteins.- Photo.- Contributors.