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Current Topics in Developmental Biology Vol 56 : Volume 56 - Gerald P. Schatten

Current Topics in Developmental Biology Vol 56

Volume 56

Hardcover

Published: 17th October 2003
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Together with other volumes in this series, Volume 56 of Current Topics in Developmental Biology presents thoughtful and forward-looking articles on developmental biology and developmental medicine.

Reviews include:

  • Selfishness in moderation: evolutionary success of the yeast plasmid
  • Nongenomic actions of androgen in sertoli cells
  • Regulation of chromatin structure and gene activity by Poly(ADP-ribose) polymerases
  • Centromeres and Kinetochores, Who Needs 'Em? The Role of Non-centromeric Chromatin in Spindle Assembly
  • Modeling Cardiogenesis: The Challenges and Promises of 3D Reconstruction
  • Plasmid and Chromosome Traffic Control: How ParA and ParB Drive Partition

The exceptional reviews in this volume of Current Topics in Developmental Biology will be valuable to both clinical and fundamental researchers, as well as students and other professionals who want an introduction to current topics in cellular and molecular approaches to developmental biology and clinical problems of aberrant development.

  • Series Editor Gerald Schatten is one of the leading minds in reproductive and developmental science
  • Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine
  • The longest-running forum for contemporary issues in developmental biology with over 30 years of coverage

Contributorsp. ix
Contribution of Membrane Mucins to Tumor Progression Through Modulation of Cellular Growth Signaling Pathways
Mucin Structure, Function, and Involvement in Tumor Progressionp. 2
MUC1 Contributions to Tumor Cell Growth Signalingp. 5
MUC4 Contributions to Tumor Cell Growth Signalingp. 10
Inhibition of Signaling by Mucinsp. 14
Perspectivesp. 15
Referencesp. 16
Regulation of the Epithelial Na[superscript +] Channel by Peptidases
Introductionp. 24
ENaC Regulation by Peptidases: In Vitro and Biochemical Evidencep. 25
ENaC Regulation by Peptidases: In Vitro Evidencep. 31
Referencesp. 41
Advances in Defining Regulators of Cementum Development and Periodontal Regeneration
Introductionp. 48
Question 1. What Are the Unknowns That Must Be Considered in Order to Replicate the Enamel (Crown) and How Do the Proteins Involved in Crown Development Relate to Root Development?p. 51
Question 2. What Do We Know About the Cells Required for Periodontal Development and Regeneration?p. 63
Question 3. What Genes and Associated Proteins Are Important for Root/Periodontal Tissue Formation?p. 76
Conclusions and Future Directionsp. 101
Acknowledgmentsp. 103
Referencesp. 103
Anabolic Agents and the Bone Morphogenetic Protein Pathway
Introductionp. 128
Bone Metabolismp. 131
The BMP Pathway and Bone Anabolic Therapiesp. 135
Conclusions and Future Directionsp. 153
Referencesp. 154
The Role of Mammalian Circadian Proteins in Normal Physiology and Genotoxic Stress Responses
Introductionp. 174
Circadian Rhythms and the Organization of the Mammalian Circadian Systemp. 175
Molecular Organization of the Circadian Oscillator in Mammalsp. 176
Human Disorders Associated with Altered Function of the Circadian Systemp. 185
Pathologies and Developmental Defects in Circadian Mutant Micep. 190
Circadian Control of the Organism's Response to Genotoxic Stressp. 200
Circadian Proteins as Targets for Therapeutic Interventionp. 207
Acknowledgmentsp. 207
Referencesp. 207
Autophagy and Cell Death
Introductionp. 218
Description of Programed Cell Death Morphologiesp. 218
Autophagic Cell Deathp. 219
Autophagy and Autophagic Cell Death Regulatory Mechanismsp. 222
Autophagy-Apoptosis Crosstalksp. 234
Survival Versus Death Aspects of Autophagyp. 236
Conclusionsp. 237
Acknowledgmentsp. 238
Referencesp. 238
Indexp. 247
Contents of Previous Volumesp. 255
Table of Contents provided by Ingram. All Rights Reserved.

ISBN: 9780121531560
ISBN-10: 0121531562
Series: Current Topics in Developmental Biology : Book 56
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 203
Published: 17th October 2003
Publisher: Elsevier Science Publishing Co Inc
Country of Publication: US
Dimensions (cm): 22.9 x 15.2  x 1.27
Weight (kg): 0.55