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Current Topics in Developmental Biology V64 : Volume 64 - Gerald P. Schatten

Current Topics in Developmental Biology V64

Volume 64

Hardcover Published: 9th December 2004
ISBN: 9780121531645
Number Of Pages: 280

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Current Topics in Developmental Biology provides a comprehensive survey of the major topics in the field of developmental biology. The volumes are valuable to researchers in animal and plant development, as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. The series has recently passed its 30-year mark, making it the longest-running forum for contemporary issues in developmental biology.
This volume contains nine important contributions from leading minds in developmental biology.
* Presents major contemporary issues and astonishing discoveries at the forefront of modern developmental biology, stem cells, cloning, and regenerative medicine
* Series Editor Gerald Schatten is one of the leading minds in reproductive and developmental science
* The longest-running forum for current issues in developmental biology with over 30 years of coverage

Contributorsp. ix
Contribution of Membrane Mucins to Tumor Progression Through Modulation of Cellular Growth Signaling Pathways
Mucin Structure, Function, and Involvement in Tumor Progressionp. 2
MUC1 Contributions to Tumor Cell Growth Signalingp. 5
MUC4 Contributions to Tumor Cell Growth Signalingp. 10
Inhibition of Signaling by Mucinsp. 14
Perspectivesp. 15
Referencesp. 16
Regulation of the Epithelial Na[superscript +] Channel by Peptidases
Introductionp. 24
ENaC Regulation by Peptidases: In Vitro and Biochemical Evidencep. 25
ENaC Regulation by Peptidases: In Vitro Evidencep. 31
Referencesp. 41
Advances in Defining Regulators of Cementum Development and Periodontal Regeneration
Introductionp. 48
Question 1. What Are the Unknowns That Must Be Considered in Order to Replicate the Enamel (Crown) and How Do the Proteins Involved in Crown Development Relate to Root Development?p. 51
Question 2. What Do We Know About the Cells Required for Periodontal Development and Regeneration?p. 63
Question 3. What Genes and Associated Proteins Are Important for Root/Periodontal Tissue Formation?p. 76
Conclusions and Future Directionsp. 101
Acknowledgmentsp. 103
Referencesp. 103
Anabolic Agents and the Bone Morphogenetic Protein Pathway
Introductionp. 128
Bone Metabolismp. 131
The BMP Pathway and Bone Anabolic Therapiesp. 135
Conclusions and Future Directionsp. 153
Referencesp. 154
The Role of Mammalian Circadian Proteins in Normal Physiology and Genotoxic Stress Responses
Introductionp. 174
Circadian Rhythms and the Organization of the Mammalian Circadian Systemp. 175
Molecular Organization of the Circadian Oscillator in Mammalsp. 176
Human Disorders Associated with Altered Function of the Circadian Systemp. 185
Pathologies and Developmental Defects in Circadian Mutant Micep. 190
Circadian Control of the Organism's Response to Genotoxic Stressp. 200
Circadian Proteins as Targets for Therapeutic Interventionp. 207
Acknowledgmentsp. 207
Referencesp. 207
Autophagy and Cell Death
Introductionp. 218
Description of Programed Cell Death Morphologiesp. 218
Autophagic Cell Deathp. 219
Autophagy and Autophagic Cell Death Regulatory Mechanismsp. 222
Autophagy-Apoptosis Crosstalksp. 234
Survival Versus Death Aspects of Autophagyp. 236
Conclusionsp. 237
Acknowledgmentsp. 238
Referencesp. 238
Indexp. 247
Contents of Previous Volumesp. 255
Table of Contents provided by Ingram. All Rights Reserved.

ISBN: 9780121531645
ISBN-10: 0121531643
Series: Current Topics in Developmental Biology
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 280
Published: 9th December 2004
Publisher: Elsevier Science Publishing Co Inc
Country of Publication: US
Dimensions (cm): 22.9 x 15.2  x 1.91
Weight (kg): 0.57
Edition Number: 74

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