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Cryptosporidium : From Molecules to Disease - Thompson


From Molecules to Disease

By: Thompson

Hardcover Published: 31st December 2003
ISBN: 9780444513519
Number Of Pages: 468

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In the relatively short period since "Cryptosporidium" was recognised as a human pathogen, and that it could be transmitted in water as well as directly between animals and people, it has been the subject of intense investigations. Its status as an opportunistic pathogen, especially in AIDS patients, and the lack of effective anti-cryptosporidial drugs have served to emphasise the public health importance of this organism. This has to some extent overshadowed the fact that "Cryptosporidium "is also an important pathogen of domestic animals and wildlife.

In recent years, the application of molecular biology and culture techniques have had an enormous impact on our understanding of the aetiological agents of cryptosporidial infections and our ability to study the causative agents in the laboratory. As a consequence, a wealth of information and novel data has been produced during the last 3-4 years, particularly in the areas of taxonomy, biology, pathogenesis, epidemiology - particularly zoonotic and water borne transmission, and treatment.

It is thus very timely to bring together in this book the international research community involved to review the major advances in research and identify the important research priorities for the future, thus enabling as wide an audience as possible to benefit from and share in this comprehensive look at "Cryptosporidium "and cryptosporidiosis.

Introduction: Cryptosporidium: from molecules to disease
Cryptosporidiosis - Aetiology, Infectivity and Pathogenesis
Cryptosporidium: they probably taste like chicken
Cryptosporidium: from molecules to disease
Cryptosporidium parvum: infectivity, pathogenesis and the host-parasite relationship
What is the clinical and zoonotic significance of cryptosporidiosis in domestic animals and wildlife
Extended Abstracts
Control of Cryptosporidium parvum infection and the role of IL-4 in two strains of inbred mice
Human peripheral CD8 + CD103 + T-lymphocyte transmigration through inverted Cryptosporidium parvum sporozoite infected HCT-8 cell monolayers
Cryptosporidium parvum volunteer study: infectivity and immunity
Transmission of human genotype 1 Cryptosporidium parvum into lambs
A longitudinal study of Cryptosporidium prevalence and its impact on performance in feedlot cattle
Identification and characterisation of the antigenic CPA135 protein
A permanent method for detecting Cryptosporidium parvum life cycle stages in in vitro culture
Successful cultivation of Cryptosporidium reveals previously undescribed Gregarino-like developmental stages
Epidemiology and species differentiation. Cryptosporidium as a public health challenge
The zoonotic potential of Cyptosporidium
Molecular epidemiology of human cryptosporidiosis
Molecular characterisation and taxonomy of Cryptosporidium
Extended Abstracts. Antigenic differences in Cryptosporidium parvum oocysts: the "Iowa strain" enigma
Antigenic analysis of Cryptosporidium parvum isolates of human and animal origin
Typing of Cryptosporidium parvum oocysts using phage-display technology
High resolution genotyping of Cryptosporidium by mutation scanning
Evaluation of oocyst DNA extraction methods using real-time PCR
Differentiation of Cryptosporidium parvum subtypes by a novel microsatelite-telomere PCR with page
Genotypic variation of Cryptosporidium organisms recovered from persons living in Kenya, Malawi, Vietnam and Brazil
Epidemiological surveys of cryptosporidiosis in Thai orphans
Cryptosporidium and Cyclospora-associated diarrhea in Kathmandu, Nepal
Ecology of zoonotic cryptosporidiosis in watersheds containing cattle farming operations
Identifying variation among human, animal and environmental isolates of Cryptosporidium
Cryptosporidium in eastern grey kangaroos Macropus giganteus
Viability and infectivity. Detection of infectious Cryptosporidium parvum oocysts in environmental water samples
Measuring inactivation of Cryptosporidium parvum by in vitro cell culture
In vitro cultivation and development of Cryptosporidium in cell culture
Extended Abstracts
The use of cell culture and real-time PCR to assess disinfection of Cryptosporidium parvum
Inactivation of Cryptosporidium parvum oocysts by low pressure UV-light
Detection of viable oocysts of
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9780444513519
ISBN-10: 0444513515
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 468
Published: 31st December 2003
Publisher: Elsevier Science & Technology
Country of Publication: GB
Dimensions (cm): 24.13 x 17.15  x 2.54
Weight (kg): 0.99