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COX-2 Inhibitors : Milestones in Drug Therapy - M. Pairet

COX-2 Inhibitors

Milestones in Drug Therapy

By: M. Pairet (Editor), J. Van Ryn (Editor)

Hardcover Published: 29th March 2004
ISBN: 9783764369019
Number Of Pages: 250

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COX-2 inhibitors are important drugs with analgesic and anti-inflammatory effects. The discovery of COX-2, the evolution of drug development in this field and the implications of these developments in patient therapy are topics of this volume. This book presents both pre-clinical and clinical information and is important for clinicians interested in the latest information about this class of drugs, for researchers and for students in the field.

The discovery of COX-2p. 1
Structural diversity of selective COX-2 inhibitorsp. 15
The molecular and biological basis for COX-2 selectivityp. 41
Pharmacology and toxicology of COX-2 inhibitorsp. 67
Efficacy and gastrointestinal safety of selective COX-2 inhibitorsp. 133
Role of COX-2 in ulcers and ulcer healingp. 149
COX-2 and the cardiovascular systemp. 161
Effects on the kidney : role of COX-2 inhibitorsp. 179
Effects on the lungs : role of COX-2 and its inhibitorsp. 195
Reproduction : role of COX-2 and its inhibitionp. 213
COX-2 in cancerp. 227
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9783764369019
ISBN-10: 3764369019
Series: Milestones in Drug Therapy
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 250
Published: 29th March 2004
Publisher: SPRINGER VERLAG GMBH
Country of Publication: CH
Dimensions (cm): 23.39 x 15.6  x 1.6
Weight (kg): 0.54