
Control of Breathing and Its Modeling Perspective
By: Yoshiyuki Honda, Oxford Conference on Control of Breathin, Y. Honda (Editor)
Hardcover | 31 January 1993
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476 Pages
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| Modelling Pioneer: Fred S. Grodins (1915-1989) | p. 1 |
| Respiratory Rhythm Genesis | |
| Maintenance of the Respiratory Rhythm during Normoxia and Hypoxia | p. 7 |
| Raphe Magnus-Induced Inhibition of Medullary and Spinal Respiratory Activities in the Cat | p. 15 |
| Cranial Nerve and Phrenic Respiratory Rhythmicity during Changes in Chemical Stimuli in the Anesthetized Rat | p. 25 |
| Possible Implication of N. Parabrachialis in Opioid-Mediated Respiratory Suppression Induced by Thin-Fiber Muscular Afferents | p. 33 |
| Synaptic and Non-Synaptic Control of Membrane Potential Fluctuations in Bulbar Respiratory Neurons of Cats | p. 43 |
| Nonlinear Dynamics of a Model of the Central Respiratory Pattern Generator | p. 51 |
| Phase-Dependent Transient Responses of Respiratory Motor Activities following Perturbation of the Cycle | p. 57 |
| Lower Lumbar and Sacral Projections of Caudal Medullary Expiratory Neurons in the Cat | p. 61 |
| Reflex Control | |
| Reflex Control of Respiratory Activity (Short Overview) | p. 65 |
| Acid Infusion Elicits Thromboxane-Mediated Cardio-Respiratory Effects | p. 71 |
| Respiratory Effects of "Renzhong Xue" in Rabbits | p. 75 |
| Effects of Hypercapnia on Nasal Reflex Responses Elicited by Nasal Insufflation of Isoflurane in Lightly-Anesthetized Humans | p. 79 |
| Electrophysiological and Anatomical Studies of the Second Order Neurons in the Reflex Pathway from Pulmonary Rapidly Adapting Receptors in the Cat | p. 83 |
| Laryngeal Afferent Activity and its Role in the Control of Breathing | p. 87 |
| Peripheral Chemosensitivity | |
| Short Overview: Carotid Body Activities in Man | p. 91 |
| Dynamical Analysis of the Ventilatory Response to Changes in PETO[subscript 2]: Separation of Central and Peripheral Effects | p. 99 |
| Single Breath Tests of the Ventilatory Response to Carbon Dioxide: Experimental and Modelling Results | p. 107 |
| Ventilatory Responses to Respiratory and Acute Metabolic Acidosis in Man | p. 115 |
| Role of Cl[superscript -]-HCO[subscript 3][superscript -] Exchanger and Anion Channel in the Cat Carotid Body Function | p. 119 |
| A Mathematical Model of the Ventilatory Response to a Period of Sustained Isocapnic Hypoxia in Humans | p. 123 |
| Carbon Dioxide - Essential Ingredient for in Vivo Carotid Body Chemotransduction | p. 127 |
| Central Chemosensitivity | |
| Hypoxic Depression of Respiration | p. 131 |
| Identification of Closed-Loop Chemoreflex Dynamics Using Pseudorandom Stimuli | p. 137 |
| Lack of Ventilatory Reaction to Endogenous and Exogenous Metabolic Brain-Stem Acidosis | p. 143 |
| Synchronization of Respiratory Rhythm with Mechanical Ventilation by Respiratory CO[subscript 2] Oscillations in Vagotomized Dogs | p. 147 |
| Factors Influencing Day to Day Variability of Human Ventilatory Sensitivity to Carbon Dioxide | p. 151 |
| Integrative and Behavioral Control | |
| Respiratory-Associated Firing of Midbrain and Thalamic Neurons: Possible Relation to the Sensation of Dyspnea | p. 155 |
| Where Is the Cortical Representation of the Diaphragm in Man? | p. 163 |
| Dyspnea and Respiratory Compensation Response to Resistive Loading in Elderly Humans | p. 167 |
| Redundancy Structures in Respiratory Control | p. 171 |
| Chemical and Non-Chemical Contributions to Breathing in Man, Awake and Asleep | p. 179 |
| Does Sustained Hypoxia Have Biphasic Effects on the Sensation of Dyspnea? | p. 183 |
| Role of Neurochemicals and Hormones | |
| Overview: Role of Neurochemicals and Hormones | p. 187 |
| The Role of Endogenous Opioids in the Ventilatory Response to Sustained Respiratory Loads | p. 197 |
| Significance of Excitatory and Inhibitory Neurochemicals in Hypoxic Chemotransmission of the Carotid Body | p. 205 |
| Role of Serotonin in Airway Patency: Physiological and Morphological Evidence for Serotoninergic Inputs to Laryngeal Inspiratory Motoneurons | p. 213 |
| Effects of Testosterone on Hypoxic Ventilatory and Carotid Body Neural Responsiveness | p. 221 |
| Effect of Theophylline on Brain Acid-Base Status during Normoxia and Hypoxia in Humans | p. 225 |
| Mechanisms of Exercise Hyperpnea | |
| Asymmetrical Transients of Cardiorespiratory Variables in Response to Ascending and Descending Ramp Forcings of Exercise Load | p. 229 |
| Dynamic Asymmetries of Ventilation and Pulmonary Gas Exchange during On- and Off-Transients of Heavy Exercise in Humans | p. 237 |
| The Effect of Exercise Intensity and Duration on Ventilation during Recovery from Moderate and Heavy Exercise | p. 245 |
| On the Fractal Nature of Breath-by-Breath Variation in Ventilation during Dynamic Exercise | p. 255 |
| The Time Course of Mixed Venous Blood Gas Composition following Exercise Onset | p. 263 |
| Humoral Aspects of the Ventilatory Reactions to Exercise by Flux Inhalation of Carbon Dioxide | p. 267 |
| Nonlinear Dynamics of Cardiopulmonary Responses during Exercise | p. 271 |
| Ventilatory Response at the Onset of Passive Exercise during Sleep in Man | p. 275 |
| Ventilatory Responses to Ascending and Descending Ramp Changes in Inspired CO[subscript 2] | p. 279 |
| Effect of Femoral Blood Flow Occlusion and Release on Ventilation during Exercise and Recovery | p. 283 |
| Hypoxic Ventilatory Depression | |
| Introduction: Depression of Ventilation by Hypoxia - A Comparison of the Phenomenon in Anaesthetized Cats and Conscious Humans | p. 287 |
| The Effects of Dopamine on the Ventilatory Response to Sustained Hypoxia in Humans | p. 291 |
| Effects of Varying End-Tidal PO[subscript 2] on Hypoxic Ventilatory Decline in Humans | p. 299 |
| Developmental Aspects of the Central Effects of Hypoxia | p. 303 |
| Modulation of Respiration by Brain Hypoxia | p. 307 |
| Respiratory Depression Following Acute Hypoxia in Vagotomized and Carotid Sinus Nerve Denervated Cats | p. 311 |
| Sleep Disorders | |
| Respiratory and Postural Suppression by Stimulation of the Midpontine Dorsal Tegmentum in Decerebrate Cats | p. 315 |
| The Role of Ventral Group Neurons in the Respiratory Depression during Carbachol-Induced REM Sleep Atonia | p. 323 |
| Control of Breathing in COPD-Patients with Sleep Hypopnea: Effects of Acetazolamide and Chlormadinone Acetate | p. 331 |
| Serial Submental Stimulation during Sleep in Patients with Obstructive Sleep Apnea | p. 337 |
| Mechanical Aspects in the Control of Breathing | |
| Effects of Viscoelastic Properties of Respiratory System on Respiratory Dynamics | p. 341 |
| Influence of Age on Ventilatory Pattern during Exercise | p. 347 |
| Abdominal Muscle Function with Change in Posture or CO[subscript 2] Rebreathing in Humans | p. 351 |
| Subacute Effects of Denervation on Rat Hemidiaphragm | p. 355 |
| Cellular and Molecular Aspects | |
| [beta]-Endorphins-Based Inhibitory Component of the Mechanism of Ventilatory Response to Hypoxia | p. 359 |
| Phosphoinositides and Signal Transduction in the Cat Carotid Body | p. 367 |
| Optimization Hypothesis | |
| Introduction: Optimization Hypothesis in the Control of Breathing | p. 371 |
| Effects of Changes in Ventilatory Pattern during Altitude Acclimatization | p. 385 |
| Optimal Control Analysis of the Breathing Pattern by Using the WBREPAT Computer Software | p. 393 |
| A Model for the Contribution of Lung Receptors to the Control of Breathing: Positive and Negative Feed-Backs | p. 397 |
| New Results in System Identification | p. 401 |
| Effects of Changes in Breathing Pattern on the Sensation of Dyspnea during Inspiratory Loaded Breathing | p. 405 |
| Role of Potassium Ion in Exercise Hyperpnea | |
| Introduction: Role of Potassium in Exercise Hyperpnoea | p. 409 |
| Acid-Base Regulation and Ventilatory Control during Exercise and Recovery in Man | p. 417 |
| Influence of Body CO[subscript 2] Stores on Ventilatory-Metabolic Coupling during Exercise | p. 425 |
| Adaption of Peripheral Chemoreceptors | |
| Respiration in Chronic Hypoxia and Hyperoxia: Role of Peripheral Chemoreceptors | p. 433 |
| Carotid Body Chemotransduction | p. 441 |
| Altitude Acclimatization and Hypoxic Ventilatory Depression: Lowlanders and Highlanders | p. 447 |
| Serial Changes in Acute Hypoxic and Hypercapnic Ventilatory Responses during High Altitude Acclimatization | p. 451 |
| Abnormal Breathing Pattern and Oxygen Desaturation during Sleep at High-Altitude | p. 455 |
| Index | p. 459 |
| Table of Contents provided by Blackwell. All Rights Reserved. |
ISBN: 9780306443008
ISBN-10: 0306443007
Published: 31st January 1993
Format: Hardcover
Language: English
Number of Pages: 476
Audience: General Adult
Publisher: Springer Nature B.V.
Country of Publication: US
Dimensions (cm): 25.4 x 17.78 x 2.69
Weight (kg): 1.04
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