Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good indepth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfor- tunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by dividing the oncology literature into specific subdivisions such as lung can- cer, genitourinary cancer, pediatric oncology, etc.
Second, by asking emi- nent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.
I. Concepts.- 1. DNA filter elution methods in anticancer drug development.- 2. Intraperitoneal chomotherapy: Principles and results of clinical trials.- II. New Drugs and New Clinical Investigation.- 3. Metabolites of tiazofurin as mediators of its biochemicaland pharmacologic effects..- 4. Extragonadal and central nervous system germ cell tumors:A review of diagnostic and therapeutic strategies.- 5. Role of preclinical pharmacology in phase I clinical trials:Considerations of schedule-dependence.- 6. Interferon: Current concepts of mechanisms of action.- 7. Acivicin: A new antimetabolite.- III. Specific Therapeutic Landmarks.- 8. Chemotherapy for malignant intracranial tumors.- 9. New antiviral compounds and impact in management of neoplastic disease and AIDS.- 10. The clinical horizon of deoxycoformycin.