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Collateral Circulation : Heart, Brain, Kidney, Limbs :  Heart, Brain, Kidney, Limbs - Wolfgang Schaper

Collateral Circulation : Heart, Brain, Kidney, Limbs

Heart, Brain, Kidney, Limbs

By: Wolfgang Schaper (Editor), Jutta Schaper (Editor)

Hardcover

Published: December 1992
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Collateral blood vessels develop by growth of pre or newly formed structures in almost all vascular provinces as a consequence of progressing stenosis of the main artery. These alternative routes of blood supply are potentially able to alter the course of vascular disease. Collateral development is a time consuming process, and arterial stenosis and occlusion often progress faster than growth of the alternative routes. The authors' ultimate goal is to provide a better understanding of collateral growth in order to pave the way for improving the conditions for these potentially selfhealing processes. These were programmed by nature but have not been perfected, probably because defenses against arterial disease had not been put under the pressure of natural selection.

Preface
List of contributors
Collateral arterial growth and reactivity: lessons from the limb and renal blood supplyp. 1
Development of the vascular system of organs and tissuesp. 17
Methods for assessing coronary collateral growth: insights into mechanisms responsible for collateral developmentp. 29
Coronary collateral development: concepts and hypothesesp. 41
Collateral vessel development in the porcine and canine heart Morphology revisitedp. 65
Angiogenesis in porcine hearts with coronary microembolizationp. 103
The role of growth factors during development of a collateral circulation in the porcine heartp. 123
Functional aspects of collateral development in animal modelsp. 149
Effect of exercise and pharmacologic interventions on coronary collateral blood flowp. 173
Function and development of coronary collateral vesselsp. 195
The role of growth factors in collateral developmentp. 215
Interactions of the coronary and collateral circulationsp. 233
Exercise induced coronary collateral development: a comparison to other models of myocardial angiogenesisp. 261
Collateral circulation of the brainp. 291
Limb collateralsp. 317
Neurohumoral and pharmacologic regulation of collateral perfusionp. 329
Venous level collaterals in the coronary systemp. 345
Microvascular collaterals in the coronary circulationp. 367
Collateral development and function in manp. 381
Indexp. 403
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9780792320128
ISBN-10: 0792320123
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 406
Published: December 1992
Publisher: Springer
Country of Publication: NL
Dimensions (cm): 23.5 x 15.5  x 2.4
Weight (kg): 0.88