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Chronic Fatigue Syndromes : The Limbic Hypothesis - Jay Goldstein

Chronic Fatigue Syndromes

The Limbic Hypothesis

Paperback Published: 10th June 1993
ISBN: 9781560249047
Number Of Pages: 286

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Chronic Fatigue Syndrome (CFS) is now a recognized major and international medical concern. Neglected for many years because of its puzzling wide range of symptoms and inability to be “slotted” into any single mainstream medical discipline, CFS has gained government, academic, and public attention. In this innovative book, Dr. Jay Goldstein provides a medical narrative of an “evolving theory” of how the symptoms of CFS may develop through dysfunction of numerous physiological pathways. He describes the biologic basis of these assumptions, and, based on an analysis of basic medical principles, leads the reader to logical conclusions. In addition, Dr. Goldstein reveals a wealth of clinical experience by describing successes and failures of various therapies and discusses the reasons for the outcomes. Dr. Goldstein's private practice is devoted to patients who fit the profile of a CFS sufferer. As a result, his extensive clinical experience has given him a unique hands-on perspective not readily available to most researchers.Chronic Fatigue Syndromes: The Limbic Hypothesis carefully reviews the extant research literature in each chapter. Although Dr. Goldstein cautions that this model should be viewed only as a PROMISING FOUNDATION for future research, no less than six peer reviewers, all leading researchers and clinicians in the CFS field, have endorsed the direction of Dr. Goldstein's bold proposition. The breadth and scope of this book is perhaps best summarized by Paul Cheney, MD, PhD, a national leader in the field:“Despite its long history, the medical establishment with its great advances in biotechnology has been largely unable to crack the basic pathophysiology of the chronic fatigue syndrome. . . . Dr. Goldstein's new book takes us to a place few people know well, and describes a plausible mechanism of injury to the deep brain which could explain every symptom seen in [patients with] chronic fatigue syndrome. . . . It is the unifying power of his hypothesis, together with emerging scientific support for this view, that makes this book an important one to read for both the patient with CFS, as well as the practitioner and medical scientist who attempt to understand it.”

Introductionp. 1
What Is Psychoneuroimmunology (PNI)?p. 15
The Limbic Systemp. 23
Limbic System Physiologyp. 28
The Limbic Zonep. 33
Chronic Fatigue Syndrome: Limbic Encephalopathy in a Dysregulated Neuroimmune Networkp. 39
Limbic Etiology of Some CFS Symptomsp. 41
Overviewp. 81
Diagnosis of Chronic Fatigue Syndromep. 95
NIH Recommendationsp. 96
Clinical Symptomsp. 98
Diagnostic Testsp. 106
Brain Function Testsp. 113
Overviewp. 122
Treatment of Chronic Fatigue Syndromep. 127
Determining Pathophysiologyp. 129
Somatization Disorderp. 147
Neuropharmacology of CFSp. 152
CFS Dementia Treatmentp. 169
Trigeminal Nerve Function and Treatmentp. 171
Pain Mechanisms and Treatmentp. 174
Alternative CFS Treatmentsp. 177
Conclusionp. 189
Addendum I: Transneuronal Retrograde Messengers in Chronic Fatigue Syndromep. 219
App.: Neuropharmacology of Chronic Fatigue Syndromep. 225
App.: Chronic Fatigue Syndrome Institute: Screening Psychological Reportp. 235
Addendum II: Is Chronic Fatigue Syndrome a Disorder of the Central Neurogenic Regulation of Cerebral Circulation?p. 239
Indexp. 247
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9781560249047
ISBN-10: 1560249048
Series: The Haworth Library of the Medical Neurobiology of Somatic Disorders, V. 1
Audience: Professional
Format: Paperback
Language: English
Number Of Pages: 286
Published: 10th June 1993
Publisher: Taylor & Francis Inc
Country of Publication: US
Dimensions (cm): 21.59 x 15.24  x 2.54
Weight (kg): 0.44
Edition Number: 1