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Chlamydia Pneumoniae and Chronic Diseases : Proceedings of the State-of-the-Art Workshop, Held at the Robert Koch-Institut Berlin, on 19 and 20 March 1999 - Johanna L'age-Stehr

Chlamydia Pneumoniae and Chronic Diseases : Proceedings of the State-of-the-Art Workshop, Held at the Robert Koch-Institut Berlin, on 19 and 20 March 1999

By: Johanna L'age-Stehr (Editor)

Paperback ISBN: 9783540411369
Number Of Pages: 203

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International specialists in Microbiology, Infectious Diseases, Internal Medicine, Cardiology Immunology, Pneumonology, Neurology and Epidemiology gathered to this workshop to discuss and enhance interdisciplinary knowledge on the possible etiological role of Chlamydia pneumoniae, a widespread human respiratory infection, in the pathogenesis of chronic inflammatory diseases with major public health impact such as atherosclerosis, cardiovascular disease, adult-onset asthma bronchiale, chronic obstructive pulmonary diseases, reactive arthritis, morbus Alzheimer and multiple sclerosis. Current deficits and goals in the standardisation of diagnostic tools, basic and applied research, design of epidemiological and monitoring of therapy studies were identified. A special feature of this book is the comprehensive collection of state-of-the-art review articles in the various fields with many references.

Introductionp. 1
Pathogenic mechanisms of chronic Chlamydia infectionsp. 3
Biology, immunology and persistence of Chlamydia pneumoniae: Links to chronic diseasep. 8
Animal models for Chlamydia pneumoniae infectionp. 19
Molecular biology and serodiagnostics of Chlamydia pneumoniae - potential way to a vaccinep. 25
Direct detection of Chlamydia pneumoniae in atherosclerotic plaquesp. 33
Detection of Chlamydia pneumoniae DNA in white blood cellsp. 42
Detection of Chlamydia pneumoniae in clinical specimens by PCR-EIAp. 48
State of the art in the diagnosis of acute and chronic Chlamydia pneumoniae infectionp. 52
Epidemiological data on respiratory tract infection with Chlamydia pneumoniae and clinical complicationsp. 63
Role of C. pneumoniae in severe asthma and COPD: Epidemiology and treatmentp. 68
Chlamydia pneumoniae in atherosclerosisp. 73
Prevalence of Chlamydia pneumoniae in human coronary plaques with acute coronary syndromep. 84
Chlamydial lipopolysaccharide and Atherosclerosisp. 91
Clinical trial designs to study antibiotic intervention in atherosclerosisp. 97
Why antibiotics against Chlamydia pneumoniae for treatment of atherosclerotic disease could failp. 103
Atherosclerosis: Why the search for a causative infectious agent is not warrantedp. 108
Chlamydia infections and arthritisp. 112
Chlamydia pneumoniae, APOE genotype, and Alzheimer's diseasep. 121
Association of Chlamydia pneumoniae with Multiple Sclerosis: Protocol for detection of C. Pneumoniae in the CSF and summary of preliminary resultsp. 137
Trends and variations of chronic diseases in populations - Can infectious agents help to solve the puzzles?p. 153
The epidemiology of Chlamydia pneumoniae versus the epidemiology of potential Chlamydial diseases (Atherosclerosis, Multiple Sclerosis, M. Alzheimer)p. 163
The high male mortality of coronary heart diseases can be explained as a result of chronic infectionp. 171
The Spandauer Gesundheitstest - Retrospective cohort study on Chlamydia pneumoniae infections and cardiovascular disease - A study conceptp. 178
Public health impact of atherosclerosis and Chlamydia pneumoniae infections - What do we know and what to expect from future researchp. 184
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9783540411369
ISBN-10: 3540411364
Audience: General
Format: Paperback
Language: English
Number Of Pages: 203
Publisher: Springer-Verlag Berlin and Heidelberg Gmbh & Co. Kg
Country of Publication: DE
Dimensions (cm): 23.39 x 15.6  x 1.22
Weight (kg): 0.32

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