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Cancer : Clinical Science in Practice: Tumor Immunology: Immunotherapy and Cancer Vaccines - A. G. Dalgleish

Cancer

Clinical Science in Practice: Tumor Immunology: Immunotherapy and Cancer Vaccines

By: A. G. Dalgleish (Editor), M.J. Browning (Editor), Karol Sikora (Foreword by)

Paperback Published: 25th November 2010
ISBN: 9780521159470
Number Of Pages: 374

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This volume reviews advances in the field of human tumor immunology, particularly in relation to the potential for immune intervention in preventing or treating tumors. The editors and contributors, all leading workers in the field, survey advances in the understanding of the relationship between the cancer cell and the immune response. Chapters review in depth the function of immune surveillance and mechanisms of tumor immunity, the role of T lymphocytes and oncogenes in the immune response to cancer, and the potential for immunotherapy of cancer. New areas of tumor immunology are presented, including recent progress in the development of tumor vaccines with particular reference to melanoma.

Review of the hardback: ' ... will serve as a good text-book on cancer immunology and/or an excellent reference source on its individual topics. It can be recommended to clinicians, researchers and even undergraduates wishing to deepen their knowledge of this field.' Anton B. Alexandfoff, Immunology News
Review of the hardback: ' ... an excellent source of information which will be most helpful to the clinicians involved or interested in the various clinical vaccine trials that have been or will be implemented in the next five years.' J.-C. Cerottini, Annals of Oncology
Review of the hardback: ' ... there is much to commend the book. It will appeal mainly to clinicians and scientists who have some basic knowledge of cancer and immunology.' J. A. Ledermann, Journal of the Royal Society of Medicine
Review of the hardback: ' ... a balanced overview of the state-of-the-art, with special emphasis on the new potential for cancer immunotherapy ... an excellent source of information'. Annals of Oncology

Contributors
Series Editor's Preface
Abbreviations
Introduction and historical perspectives
The immunosurveillance of cancer: specific and non-specific mechanisms
Antigen processing and presentation
The role of the MHC class I in tumor immunity
Human tumor antigens recognized by Cytolytic T Lymphocytes
Peptide-specific CTL directed against viral oncogene products Mariet
Cellular oncogenes for tumor immunity: immunotherapy
Co-stimulatory molecules and their role in tumour immunity
The role of cytokines in tumour rejection
Inhibition of nonhemopoietic cancer cell growth by Interleukin-4 and related cytokines
Current concepts concerning melanoma vaccines
Immune responses to mucins Rosalind
Heat shock protein-peptide complexes: pan-valent vaccines against cancers and infectious diseases
The potential of gene transfer to alter the immune response to tumors
Applications of antibody gene technology
Index
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9780521159470
ISBN-10: 0521159474
Series: Cancer: Clinical Science in Practice
Audience: Professional
Format: Paperback
Language: English
Number Of Pages: 374
Published: 25th November 2010
Publisher: Cambridge University Press
Country of Publication: GB
Dimensions (cm): 22.9 x 15.2  x 2.1
Weight (kg): 0.55