In this book, 16 leading authorities examine brain cholinergic systems from their standpoints in the fields of morphology, immunohistochemistry, electrophysiology, behaviour and cognitive disorders. The book covers major aspects of the organization and connectivity of cholinergic systems at the light - and electron-microscopic - levels, intrinsic electrophysiological properties and ionic conductances of central cholinergic and cholinoceptive neurons, the effects of brainstem and basal forebrain cholinergic systems upon thalamic and cortical neurons, plasticity processes in the thalamins and cerebal cortex and studies on Alzheimer's disease. As such, this volume may be of interest to morphologists, physiologists, psychologists and clinicians.
PART 1: NEW VISTAS ON THE ASCENDING CHOLINERGIC ACTIVATION: M. Steriade & G. Buzsaki: Parallel activation of thalamic and cortical neurons by brainstem and basal forebrain cholinergic systems; PART 2: MORPHOLOGICAL ORGANIZATION OF CHOLINERGIC SYSTEMS; B.H. Wainer & M.-M. Mesulam: Ascending cholinergic pathways in the rat brain; V.E. Koliatsos, L.E. Martin, & D.L. Price: Efferent organization of the mammalian basal forebrain; D.
Fitzpatrick & D. Raczkowski: The morphology of cholinergic projections from the brainstem reticular formation of the lateral geniculate nucleus and other thalamic nuclei in the cat; F. Heft, J. Hartikka, B. Knusel, M.O. LaPlume, &
D.C. Mash: Nerve growth factor and cholinergic neurons of the mammalian brain; PART 3: PHYSIOLOGICAL ASPECTS OF CHOLINERGIC SYSTEMS: C.S. Leonard & R.R. Llinas: Electrophysiology of mammalian pedunculopontine and laterodorsal tegmental neurons in vitro: implications for the control of REM sleep; R.W. Green & R.W. McCarley: Cholinergic transmission in the brainstem: implications for behavioural state control; D.A. McCormick: Cellular mechanisms of cholinergic control of
necortical and thalamic neuronal excitability; Y. Lamour, M.C. Senut, M.H. Bassant, & P. Dutar: Functional properties of septo-hippocampal neurons; R.T. Richardson & M.R. DeLong: Responses of primate nucleus basalis neurons to
water rewards and related stimuli; R.W. Dykes: Acetylcholine and neuronal plasticity in somatosensory cortex; W. Singer: The role of acetycholine in use-dependent plasticity of the visual cortex; D. Pare & M. Steriade: Control of the mammilothalmic axis by brainstem cholinergic laterodorsal tegmental afferents: possible involvement in mnemonic processes; PART 4: DISORDERS WITH COGNITIVE DECLINE: G. Pepeu, P.L. Di Patre, & F. Casamenti: Spontaneous and drug-stimulated recovery of
cortical cholinergic function after lesion of the nucleus basalis; V. Bigl, T. Arendt, & D. Biesold: The nucleus basalis of meynert during ageing and in dementing neuropsychiatric disorders; N.J. Woolf & L.L.
Butcher: Disdifferentiation of structurally plastic neurons initiates the pathologic cascade of Alzheimer's disease: toward a unifying hypothesis.
Number Of Pages: 468
Published: 29th November 1990
Publisher: Oxford University Press
Country of Publication: GB
Dimensions (cm): 28.0 x 22.2
Weight (kg): 1.67