It is an exciting time to follow the new developments in the field of biotechnology and its wider applications in the different areas. The whole genomes of over 1000 viruses and over 100 microbes can now be found in Entrez Genome. The genomes represent both completely sequenced organisms and those for which sequencing is still in progress. The three main domains of life - bacteria, archaea, and eukaryota - are represented, as well as many viruses and organelles.
The exponential increase of the sequence data lead to the development of the new "Bioinformatics" field in order to attempt making sense, at least biological sense, out of all the new and fast data.
It will take also other techniques such as "functional genomics" to link the gap between a specific phenotype or a treatment and a gene sequence. Functional genomics tools are therefore important for the accurate molecular diagnosis/prognosis, target discovery validation needed for drug development and novel targets for antibiotics development. Functional genomics are also important for the confirmation of therapy in pharmacogenomics studies.
Biotechnology is in many respects shaping our life and affecting our means of production and the creation of jobs. Progress in the applications of biotechnology depends on a wide base of basic as well as applied sciences. The output of biotechnology has already proved itself in many diverse fields from health to
biomining and from agriculture to enzyme "breeding". It is therefore difficult to follow all of the current as well as the potential applications of biotechnology.
The objective of the Biotechnology Annual Review series is to attempt to provide readers with the needed indepth knowledge, by reviewing specific topics in biotechnology in each issue. The philosophy behind this series is to encourage good reviews to make it easier for readers to keep in touch with progress and applications of biotechnology. Reviews on topics related to regulatory affairs, social impact of biotechnology, biodiversity, biosafety, public acceptance and patent issues are also encouraged.
|Two-dimensional DNA electrophoresis: state of the art and applications|
|The two-hybrid system in yeast: applications in biotechnology and basic research|
|Human gene therapy: principles and modern advances|
|Group I introns in biotechnology: prospects of application of ribozymes and rare-cutting homing endonucleases|
|Development of recombinant vaccines against infectious bursal disease|
|Molecular methods in diagnostic pathology|
|Transgenic manipulation of signaling pathways of plant resistance to pathogen attack|
|Production and characterization of double-layer beads for coimmobilization of microbial cells|
|Molecular genetic improvement of salt tolerance in plants|
|Plant promoters for transgene expression|
|Recombinant Gram-positive bacteria as vehicles of vaccine antigens|
|The expression of Bacillus thuringiensis toxin genes in plant cells|
|Index of Authors|
|Table of Contents provided by Publisher. All Rights Reserved.|
Series: Biotechnology Annual Review : Book 9
Number Of Pages: 434
Published: 9th October 2003
Publisher: Elsevier Science & Technology
Country of Publication: GB
Dimensions (cm): 24.13 x 17.15 x 2.54
Weight (kg): 1.13