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Biomolecular NMR Spectroscopy - Jeremy N. S. Evans

Biomolecular NMR Spectroscopy

Paperback Published: 28th September 1995
ISBN: 9780198547662
Number Of Pages: 460

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The technique of nuclear magnetic resonance (NMR) spectroscopy is an important tool in biochemistry and biophysics for the understanding of the structure and, ultimately, the function of biomolecules. This textbook explains the salient features of biological NMR spectroscopy to undergraduates and postgraduates taking courses in NMR, 4iological NMR, physical biochemistry, and biophysics. Unlike other books in the general field of NMR (except the advanced treatises), the approach here is to introduce and make use of quantum mechanical product operators as well as the classical vector method of explaining the bewildering array of pulse sequences available today. The book covers two-dimensional, three-dimensional, and four-dimensional NMR, and their application to protein and DNA structure determination. A unique feature is the coverage of the biological aspects of solid-state NMR spectroscopy. The author provides many selected examples from the research literature, illustrating the applications of NMR spectroscopy to biological proteins.

Industry Reviews

`... written in a vibrant, enthusiastic style ... It will appeal to a wide readership, from undergraduate chemists ... biochemists and some biologists, to postdoctoral scientists working in this specialized field ... it is good value.' Chemistry in Britain, February 1996 `a very useful book ... I plan on using this book in my course for the foreseeable future and I highly recommend Biomolecular NMR Spectroscopy to you.' Kevin H. Mayo, University of Minnesota Health Sciences Center, Biophysical Journal, Volume 70, June 1996 `The author writes clearly and enthusiastically ... the strength of the book is its broad coverage of scores of applications of NMR to important biological problems ... Another positive aspect of Biomolecular NMR Spectroscopy is the care with which the author places NMR in the context of the larger scientific picture.' Patricia J. Lodi, nature structular biology volume 3 number 5 may 1996

Part 1: Theory Introduction 1: Methods for spectral assignment - multidimensional NMR 2: Obtaining NMR structures Part II: Proteins 3: Protein structure 4: Protein folding Part III: Enzymes 5: Enzyme function 6: Acyl and phosphoryl transfer enzymes 7: Other enzymes Part IV: Nucleic Acids and Carbohydrates 8: Nucleic acids and carbohydrates Part V: Membranes 9: Structure of membranes and membrane proteins Appendix 1 Examples of product operator calculations Appendix 2 Useful NMR data on amino acid residues Appendix 3 Useful NMR data on oligonucleotide residues Appendix 4 Useful NMR data on common solvents Index

ISBN: 9780198547662
ISBN-10: 0198547668
Audience: Professional
Format: Paperback
Language: English
Number Of Pages: 460
Published: 28th September 1995
Publisher: Oxford University Press
Country of Publication: GB
Dimensions (cm): 25.4 x 19.68  x 2.54
Weight (kg): 0.96

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