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Biology of Negative Strand RNA Viruses : The Power of Reverse Genetics - Yoshihiro Kawaoka

Biology of Negative Strand RNA Viruses

The Power of Reverse Genetics

By: Yoshihiro Kawaoka (Editor)

Hardcover

Published: 7th May 2004
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Negative-strand RNA viruses, so named because of the polarity of their genomic RNA to mRNA, include important human and non-human pathogens. This volume covers major advances in reverse genetics techniques over the past decade, state-of-the-art basic science and the clinical implications of experimental findings. This should rekindle interest in negative-strand RNA viruses among readers, including those in other disciplines, leading to further progress in understanding these important viruses and in developing effective measures of control.

Introduction
Reverse genetics of mononegavirales
Reverse systems for the generation of segmented negative-sense RNA viruses entirely from cloned cDNA
Transcription and replication of non-segmented negative strand RNA viruses
Orthomyxovirus replication, transcription, and polyadenylation
Escaping from the cell: assembly and budding of negative-strand RNA viruses
Accessory genes of the paramyxoviridae, a large family of nonsegmented negative strand RNA viruses, as a focus of active investigation by reverse genetics
Identification and characterization of viral antagonists of type I interferon in negative-strand RNA viruses
Towards multivalent vaccines and therapeutic viruses
Influenza vaccines generated by reverse genetics
Subject index
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9783540406617
ISBN-10: 3540406611
Series: Current Topics in Microbiology and Immunology
Audience: Tertiary; University or College
Format: Hardcover
Language: English
Number Of Pages: 350
Published: 7th May 2004
Publisher: Springer-Verlag Berlin and Heidelberg Gmbh & Co. Kg
Country of Publication: DE
Dimensions (cm): 23.5 x 15.5  x 2.54
Weight (kg): 0.77