Biology of Brain Tumor

Section I. Molecular Neurooncology.- 1. Molecular Biology of Cancer.- 2. Two-Dimensional Gel Electrophoretic Protein Patterns in High-Grade Human Astrocytomas.- 3. Biochemical Studies of Primary Cultures from Human Astrocytomas: Observations on Cell Growth and Regulation of Glutamine Synthetase.- 4. Dibutyryl Adenosine 3?:5?-Cyclic Monophosphate (db-cAMP) Induced Growth Inhibition and Morphologic Changes in Human Medulloblastoma Cell line TE671.- 5. Phenotypic Modification of Human Glioma.- 6. Chromosomes and Chromosomal Progression of Malignant Human Gliomas: Theoretical and Practical Implications.- 7. Differential Expression of Neuron Specific Enolase and Creatine Phosphokinase-BB by Human Medulloblastoma and Glioma Tumors and Neuroectodermal Cell Lines.- 8. Neovascularisation of Intracranial Tumours.- 9. Red Blood Cell Polyamines in Malignant Glioma Patients. Spermidine and Spermine Blood Levels and Tumour Evolution..- Section II. Modern Neuropathology.- 10. Pathological Classification of Tumours of the Central Nervous System.- 11. Modem Neuropathological Investigative Techniques of Brain Tumours.- 12. Adenylate Cyclase Activity and Cyclic AMP Content in Human Central Nervous System Tumors and in Cerebrospinal Fluid of Patients Bearing Brain Tumors.- 13. Non-Nuclear Cytotoxic Actions of DNA Cross-Linking and/or Alkylating Agents in Glioma- Derived Cell Lines.- 14. Intracerebral Transplantation of D-54 MG Human Glioma Line in Immunosuppressed Rats.- 15. In vivo Characterization of a Human Neuroectodermal Tumor Cell Line.- 16. Carbonic Anhydrase C as a Marker Antigen in the Diagnosis of Choroid Plexus Papillomas and Other Tumours: An Immunoperoxidase Study.- 17. Transplacental ENU Tumors of the Rat: Immunohistochemical Contribution to the Recognition of Cell Types.- 18. Vascularization of Human Cerebral Gliomas: A Lectin-Cytochemical and Morphometric Study.- 19. Immunohistochemical Demonstration of HLA-DR Positive Cells in Normal and Neoplastic Brain Tissues. I. Preliminary Report.- 20. Primary Non-Hodgkin Lymphomas of the Central Nervous System.- 21. Evaluation of a Transplantable Mouse Brain Tumour: A Model for the Study of Human Glioma.- Section III. Correlates of Brain Tumour Imaging.- 22. Neuropathology and Imaging. The Ways in Which Glioma Spreads and Varies in Its Histological Aspect.- 23. Magnetic Resonance Imaging of Central Nervous System Tumors.- 24. Radioimmunolocalisation of Primary Cerebral Tumours in Humans.- 25. Histological Factors in the Prognosis of Malignant Astrocytomas.- 26. Correlation of Target Site with Histology and Cell Culture in CT-directed Stereotactic Biopsy.- 27. The Vasculature of Experimental Brain Tumours: Angiogenesis, Vascular Pathology and Per-meability Studies.- 28. An Autoradiographic Approach for Studying the Distribution of Neurotransmitter Receptor Binding Sites on Biopsy Samples of Human Gliomas.- 29. Drug Delivery to Brain Tumors: Physiological and Pharmacokinetic Aspects of Chemotherapy.- 30. Experimental Models of Rat Brain Tumors by Stereotactic Injection of C6 Glioma and HTC Hepatoma Cell Lines.- 31. Cerebral Infarction as a Result of Tumor Emboli.- Section IV. Surgical Neurooncology.- 32. Technical Approaches to Identification and Stereotactic Reduction of Tumor Burden.- 33. A Surgical History of Maida Vale Hospital.- 34. Pre-Operative Stereo-Scanning for Glioma Treatment Planning.- 35. Stereotactic Curietherapy of Thalamic Tumours.- 36. Intraoperative Radiation Therapy for Glioblastoma Multiforme.- 37. 'Radical' Surgical Decompression of Supratentorial Gliomas. Do the Results Justify the Opera-tion?.- 38. Laser Microsurgery: A Review of 110 Tumors of the Brain and Spinal Cord.- 39. Carbon Dioxide Laser Surgery For Malignant Glioma.- 40. Long Term Results of Ventricular Shunts Performed Prior to Posterior Fossa Operation for Tumor.- 41. Radical Laser Surgery in the Treatment of Gliomas.- 42. Preliminary Observation on the Use of the Local Thermochemotherapy in the Treatment of Malignant Cerebral Tumors.- 43. Remarks on the Surgical Treatment of Bilateral Transcallosal Gliomas.- Section V. The Biology of Radiotherapy.- 44. Radiation Damage to Brain and Cranial Soft Tissues: Outcome and Incidence Before and After Reduction in Dose.- 45. Radiotherapy with a Three-Fraction Per Day Regimen in a Split Course of Irradiation for Malignant High Grade Astrocytomas.- 46. Non-Invasive Thermochemotherapy for Advanced Brain Tumors.- 47. 252CF Neutron Brachytherapy for Malignant Glioma at the University of Kentucky and a Malig-nant Glioma Therapeutic Staging System.- 48. Permanent Radioactive Iodine Seed Implants Following Radical Resection in Recurrent Human Malignant High Grade Astrocytomas.- 49. Technique and Preliminary Results of Interstitial Irradiation for Recurrent Glial Tumors.- 50. Results of Definitive Irradiation for Optic Gliomas.- Section VI. Drug Therapy.- 51. Current Approaches to Chemotherapy.- 52. Cisplatin, Arabinofuranosyl Cytosine, and Caffeine Before Radiation for Glioblastomas.- 53. Multimodality Therapy of Supratentorial High-Grade Gliomas.- 54. The Use of Experimental Models of Human Medulloblastoma in the Design of Rational Therapy.- 55. Phase II Study of Novantrone (Mitoxantrone Hydorchloride) in Adults with Grade III-IV Astrocytomas.- 56. An Experimental Study of Xenografted Human Gliomas.- 57. Human Central Nervous System Pharmacology of Tiazofurin.- 58. Primary Therapy of Medulloblastoma with Surgery, Radiation, and Methotrexate and BCNU - A Pilot Study.- 59. Cyclophosphamide, Adriamycin, Vincristine, and Dexamethasone in the Treatment of Bulky Central Nervous System Lymphoma.- 60. Effect of Intracarotid Administration of BCNU in Rats.- 61. Intravenous and Subarachnoid Adriamycin in Experimental Meningeal Carcinomatosis: Tissue Concentration and Therapeutic Efficacy.- 62. Adriamycin in the Treatment of Malignant Meningiomas.- 63. Heterogeneity in Response of Short-Term Glioma Cell Cultures to Cytotoxic Drugs: Correlation of In Vitro Chemosensitivity and Relapse Free Interval.- 64. High Dose Polichemotherapy with Autologous Bone Marrow Transplantation in Recurrent Medulloblastoma. A Pilot Study.- 65. Phase I Study of Intraarterial Mitomycin-C for Recurrent Intracerebral Tumors.- 66. In Vitro Phase II Trial with the Human Tumor Stem Cell Assay as a New Brain Tumor Model for Drug Screening: Preliminary Results.- Section VII. Immunoneurobiology.- 67. Immunotherapy of Patients with Brain Tumors - Current Prospective.- 68. Effect of Interferons and an Interferon Inducer on Malignant Brain Tumors.- 69. Antigenic Heterogeneity of Human Glioma Tissue and Cell Lines (HGL) Defined by Monoclonal Antibodies (MAs).- 70. T-Cell Mediated Cytotoxicity in Human Glioma.- 71. Modulation of HLA-DR Expression and Growth Inhibition on Glioma Cells: Heterogeneous Responses to Interferon.