Biological Membrane Ion Channels

Dynamics, Structure, and Applications

By: Shin-Ho Chung (Editor), Olaf S. Anderson (Editor), Vikram V. Krishnamurthy (Editor)

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Hardcover | 13 December 2006

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Hardcover
676 Pages

Dimensions(cm)
24.13 x 16.51 x 3.18

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Ion channels are biological nanotubes that are formed by membrane proteins. Because ion channels regulate all electrical activities in living cells, understanding their mechanisms at a molecular level is a fundamental problem in biology. This book deals with recent breakthroughs in ion-channel research that have been brought about by the combined effort of experimental biophysicists and computational physicists, who together are beginning to unravel the story of these exquisitely designed biomolecules. With chapters by leading experts, the book is aimed at researchers in nanodevices and biosensors, as well as advanced undergraduate and graduate students in biology and the physical sciences.

Key Features

Presents the latest information on the molecular mechanisms of ion permeation through membrane ion channels
Uses schematic diagrams to illustrate important concepts in biophysics
Contains a CD-ROM with computer programs used for making theoretical calculations, as well as video animations illustrating various features of ion channels
Written by leading researchers in the area of ion channel investigations

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You Can Find This Book In

Non-Fiction Science Physics Applied Physics Biophysics Medicine Clinical & Internal Medicine Neurology & Clinical Neurophysiology Engineering & Technology Biochemical Engineering Biotechnology Biology, Life Sciences

Biochemistry Zoology & Animal Sciences Cellular Biology Pre-Clinical Medicine & Basic Sciences

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Paperback

Published: 12th February 2010

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Preface	p. v
List of Contributors	p. xi
Introduction
Ion Channels, from Fantasy to Fact in Fifty Years	p. 3
Specific Channel Types
Gramicidin Channels: Versatile Tools	p. 33
Voltage-Gated Ion Channels	p. 81
Voltage-Gated Potassium Channels	p. 119
BK[subscript Ca]-Channel Structure and Function	p. 171
Voltage-Gated Sodium Channels	p. 219
Calcium Channels	p. 241
Chloride Transporting CLC Proteins	p. 301
Ligand-Gated Ion Channels: Permeation and Activation	p. 335
Mechanosensitive Channels	p. 369
TRP Channels	p. 399
Ion Channels in Epithelial Cells	p. 425
Theoretical Approaches
Poisson-Nernst-Planck Theory of Ion Permeation Through Biological Channels	p. 449
A Mesoscopic-Microscopic Perspective on Ion Channel Permeation Energetics: The Semi-Microscopic Approach	p. 485
Brownian Dynamics Simulation for Ion Channel Permeation	p. 507
Molecular Dynamics Simulation Approaches to K Channels	p. 545
Emerging Technologies
Patch-Clamp Technologies for Ion Channel Research	p. 571
Gated Ion Channel-Based Biosensor Device	p. 595
Signal Processing Based on Hidden Markov Models for Extracting Small Channel Currents	p. 623
Index	p. 651
Table of Contents provided by Ingram. All Rights Reserved.

Biological Membrane Ion Channels

Dynamics, Structure, and Applications

At a Glance

Hardcover

Shipping

How to return your order

Defective items

You Can Find This Book In

Other Editions and Formats

Paperback

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