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Bioinformatics Research and Applications : 6th International Symposium, Isbra 2010, Storrs, Ct, Usa, May 23-26, 2010. Proceedings - Mark Borodovsky

Bioinformatics Research and Applications

6th International Symposium, Isbra 2010, Storrs, Ct, Usa, May 23-26, 2010. Proceedings

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Published: 6th May 2010
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th The 6 International Symposium on Bioinformatics Research and Applications (ISBRA2010)washeldduringMay23-26,2010attheUniversityofConnecticut, Storrs, Connecticut. The symposium provided a forum for the exchange of new results and ideas among researchers, developers, and practitioners working on all aspects of bioinformatics, computational biology, and their applications. The program of the symposium included 20 contributed papers selected by the ProgramCommittee from 57 submissions received in response to the call for papers. The symposium also included poster presentations and featured invited keynote talks by six distinguished speakers: Catalin Barbacioru from Life Te- nologies spoke on tracing the early cell divisions of mouse embryos by single cell RNA-seq, Piotr Berman from Pennsylvania State University spoke on successes and failures of elegant algorithms in computational biology, Mark Gerstein from Yale University spoke on human genome annotation, Ivan Ovcharenko from the National Center for Biotechnology Information spoke on the structure of pro- mal and distant regulatory elements in the human genome, Laxmi Parida from the IBM T. J. Watson Research Center spoke on combinatorics in recombi- tional population genomics, and Mona Singh from Princeton University spoke on predicting and analyzing cellular networks. We would like to thank the Program Committee members and external - viewers for volunteering their time to review and discuss symposium papers.

Tracing the Early Cell Divisions of Mouse Embryos by Single Cell RNA-Seq (Invited Keynote Talk)p. 1
Successes and Failures of Elegant Algorithms in Computational Biology (Invited Keynote Talk)p. 2
Modeling without Borders: Creating and Annotating VCell Modelsp. 3
Using the Webp. 18
Touring Protein Space with Mattp. 29
Fixed-Parameter Algorithm for General Pedigrees with a Single Pair of Sitesp. 29
Analysis of Temporal-spatial Co-variation within Gene Expression Microarray Data in an Organogenesis Modelp. 38
Human Genome Annotation (Invited Keynote Talk)p. 50
Extensions and Improvements to the Chordal Graph Approach to the Multi-state Perfect Phylogeny Problemp. 52
Analysis of Gene Interactions Using Restricted Boolean Networks and Time-Series Datap. 61
Residue Contexts: Non-sequential Protein Structure Alignment Using Structural and Biochemical Features
Essential Proteins Discovery from Weighted Protein Interaction Networksp. 89
Identifying Differentially Abundant Metabolic Pathways in Metagenomic Datasetsp. 101
A Novel Approach for Compressing Phylogenetic Treesp. 113
Structure of Proximal and Distant Regulatory Elements in the Human Genome (Invited Keynote Talk)p. 125
Combinatorics in Recombinational Population Genomics (Invited Keynote Talk)p. 126
Uncovering Hidden Phylogenetic Consensusp. 128
An Agglomerate Algorithm for Mining Overlapping and Hierarchical Functional Modules in Protein Interaction Networksp. 140
Fast Protein Structure Alignmentp. 152
Predicting and Analyzing Cellular Networks (Invited Keynote Talk)p. 166
A Consensus Tree Approach for Reconstructing Human Evolutionary History and Detecting Population Substructurep. 167
Inferring Evolutionary Scenarios for Protein Domain Compositionsp. 179
Local Structural Alignment of RNA with Affine Gap Modelp. 191
Fast Computation of the Exact Hybridization Number of Two Phylogenetic Treesp. 203
"Master-Slave" Biological Network Alignmentp. 215
Deciphering Transcription Factor Binding Patterns from Genome-Wide High Density ChIP-chip Tiling Array Datap. 230
The Expected Fitness Cost of a Mutation Fixation under the One-Dimensional Fisher Modelp. 241
Author Indexp. 253
Table of Contents provided by Ingram. All Rights Reserved.

ISBN: 9783642130779
ISBN-10: 3642130771
Series: Lecture Notes in Bioinformatics
Audience: General
Format: Paperback
Language: English
Number Of Pages: 252
Published: 6th May 2010
Publisher: Springer-Verlag Berlin and Heidelberg Gmbh & Co. Kg
Country of Publication: DE
Dimensions (cm): 23.37 x 15.49  x 1.52
Weight (kg): 0.41