+612 9045 4394
Bioinformatics of Genome Regulation and Structure - Nikolay Kolchanov

Bioinformatics of Genome Regulation and Structure

By: Nikolay Kolchanov (Editor), Ralf Hofestaedt (Editor)

Hardcover Published: 31st January 2004
ISBN: 9781402077357
Number Of Pages: 374

Share This Book:


RRP $628.99
or 4 easy payments of $108.94 with Learn more
Ships in 7 to 10 business days

Other Available Editions (Hide)

Bioinformatics of Genome Regulation and Structure covers: - regulatory genomic sequences: databases, knowledge bases, computer analysis, modeling, and recognition; - large-scale genome analysis and functional annotation; - gene structure detection and prediction; - comparative and evolutionary genomics; - computer analysis of genome polymorphism and evolution; computer analysis and modeling of transcription, splicing, and translation; structural computational biology: structure-function organization of genomic DNA, RNA, and proteins; - gene networks, signal transduction pathways, and genetically controlled metabolic pathways: databases, knowledge bases, computer analysis, and modeling; principles of organization, operation, and evolution; - data warehousing, knowledge discovery and data mining; and, analysis of basic patterns of genome operation, organization, and evolution. The data presented may be used while solving a wide range of problems, both basic and applied, in various directions of molecular biology, molecular genetics, biotechnology, pharmacogenetics, pharmacology, and adjacent fields of medicine, veterinary, and agrobiology.

Contributing Authorsp. XI
Prefacep. XIII
Forewordp. XV
Computational Genomicsp. 1
Nucleosomal DNA Organization: An Integrated Information Systemp. 3
Using Change in Local DNA Sequence Complexity as a Pointer to the Mechanism of Mutagenesis in Inherited Diseasep. 13
Properties of Insertion Regions of Drosophila LTR Retrotransposonsp. 21
Compositional Asymmetries and Predicted Origins of Replication of the Saccharomyces Cerevisiae Genomep. 33
Revealing and Functional Analysis of tRNA-like Sequences in Various Genomesp. 39
Type-Specific Features of the Structure of the tRNA Gene Promotersp. 47
Mathematical Tools for Regulatory Signals Extractionp. 61
Argo_Viewer: A Package for Recognition and Analysis of Regulatory Elements in Eukaryotic Genesp. 71
Transcription Regulatory Regions Database (TRRD): Description of Transcription Regulation and the Main Capabilities of the Databasep. 81
Sitecon--A Tool for Analysis of DNA Physicochemical and Conformational Properties: E2F/DP Transcription Factor Binding Site Analysis and Recognitionp. 93
Local Secondary Structure may be a Critical Characteristic Influencing Translation of Unicellular Organisms mRNAp. 103
Computer Analysis of miRNA-mRNA Duplexes and its Application to Predicting Possible Target mRNAS of Arabidopsisp. 115
Correlations Between Sequence Features of Yeast Genes Functional Regions and the Level of Expressionp. 125
Computational Structural Biologyp. 133
Latent Periodicity of Many Domains in Protein Sequences Reflects their Structure, Function, and Evolutionp. 135
Logical Analysis of Data as a Predictor of Protein Secondary Structuresp. 145
Structure-Specificity Relationship in Protein-DNA Recognitionp. 155
Macromolecular Modeling as a Tool for Expanding Bioinformatics Databasesp. 163
Graphic Representation of Equilibrium and Kinetics in Oligopeptides: Time-Dependent Free Energy Disconnectivity Graphsp. 171
Solvent Electrostatic Screening in Protein Simulationsp. 179
Pdbsitescan: A Program Searching for Functional Sites in Protein 3D Structuresp. 185
A Genetic Algorithm for the Inverse Folding of RNAp. 193
Signal Transduction Pathways Initiated VIA Cell Surface Receptor CD150: In Silico and in Vitro Analysisp. 203
Computational Evolutionary Biologyp. 211
Study of the Specific Contextual Features of Translation Initiation and Termination Sites in Saccharomyces Cerevisiaep. 213
Contribution of Coordinated Substitutions to the Constancy of Physicochemical Properties of ATP-Binding Loop in Protein Kinasesp. 223
Sporadic Emergence of Latent Phenotype During Evolutionp. 231
Similarity Analysis of Inversion Banding Sequences in Chromosomes of Chironomus Species (Breakpoint Phylogeny)p. 245
System Computational Biologyp. 255
Integrative Analysis of Gene Networks Using Dynamic Process Pattern Modellingp. 257
Development and Analysis of Models of Genetic and Metabolic Networks and Signal Transduction Pathways in the Genenet Systemp. 265
Extension of Cell Cycle Gene Network Description Based on Prediction of Potential Binding Sites for E2F Transcription Factorp. 273
Mathematical Simulation of Dynamics of Macrophage Gene Network Activated by Lipopolysaccharides and/or Interferon-gp. 283
Computer Dynamic Modeling of the Gene Network Controlling Intracellular Cholesterol Homeostasisp. 293
An Investigation of the Structural Stability of Drosophila Control Gene Subnetwork in Computer Experimentsp. 301
Modeling Plant Development with Gene Regulation Networks Including Signaling and Cell Divisionp. 311
The Global Operation Modes of Gene Networks Determined by the Structure of Negative Feedbacksp. 319
Statistical Analysis of Microarray Data: Identification and Classification of Yeast Cell Cycle Genesp. 331
Referencesp. 343
Indexp. 371
Table of Contents provided by Rittenhouse. All Rights Reserved.

ISBN: 9781402077357
ISBN-10: 1402077351
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 374
Published: 31st January 2004
Publisher: Springer-Verlag New York Inc.
Country of Publication: US
Dimensions (cm): 23.5 x 15.5  x 3.18
Weight (kg): 1.61