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Biochemistry : 6th Edition - Reginald H. Garrett

Hardcover Published: 1st January 2016
ISBN: 9781305577206
Number Of Pages: 1280

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Continuing Garrett and Grisham's innovative conceptual and organizing "Essential Questions" framework, Biochemistry guides students through course concepts in a way that reveals the beauty and usefulness of biochemistry in the everyday world. Offering a balanced and streamlined presentation, this edition has been updated throughout with new material and revised presentations.

For the first time, this book is integrated with OWLv2, a powerful online learning system for chemistry with book-specific end-of-chapter material that engages students and improves learning outcomes.

New to the Edition

  • Brand NEW “Deeper Look” Boxes have been added to Chapters 3, 4, 6, 7, 11, 12, 18, 23, and 30.


  • Brand NEW “Human Biochemistry” Boxes have been added to Chapters 7, 14, 16, 18, 19, 20, 24, and 26.


  • Brand NEW “Critical Developments in Biochemistry” Boxes in Chapters 4, 5, 6, 12, and 14.


  • Entirely new sections have been added to Chapters 5 and 12.


  • MANY New figures have been added and revised throughout.




About the Author

Reginald H. Garrett was educated in the Baltimore city public schools and at the Johns Hopkins University, where he received his Ph.D. in biology in 1968. Since that time, he has conducted research and taught biochemistry courses at the University of Virginia, where he is currently Professor of Biology. He is the author of numerous papers and review articles on biochemical, genetic, and molecular biological aspects of inorganic nitrogen metabolism. His early research focused on the pathway of nitrate assimilation in filamentous fungi. His investigations contributed substantially to our understanding of the enzymology, genetics, and regulation of this major pathway of biological nitrogen acquisition. More recently, he has collaborated in systems approaches to the metabolic basis of nutrition-related diseases. His research has been supported by grants from the National Institutes of Health, the National Science Foundation, and private industry. A member of the American Society for Biochemistry and Molecular Biology, Garrett is a former Fulbright Scholar, was twice Visiting Scholar at the University of Cambridge, and was Invited Professor at the University of Toulouse, France.

Charles M. Grisham received his B.S. in chemistry from the Illinois Institute of Technology in 1969 and his Ph.D. in chemistry from the University of Minnesota in 1973. Following a postdoctoral appointment at the Institute for Cancer Research in Philadelphia, he became Professor of Chemistry at the University of Virginia, where he teaches biochemistry, introductory chemistry, and physical chemistry. He has authored numerous papers and review articles on active transport of sodium, potassium, and calcium in mammalian systems, on protein kinase C, and on the applications of NMR and EPR spectroscopy to the study of biological systems. His work has been supported by the National Institutes of Health, the National Science Foundation, the Muscular Dystrophy Association of America, the Research Corporation, the American Heart Association and the American Chemical Society. A member of the American Society for Biochemistry and Molecular Biology, Grisham held the Knapp Chair in Chemistry in 1999 at the University of San Diego; was Visiting Scientist at the Aarhus University Institute of Physiology, Aarhus, Denmark, for two years; and received a Research Career Development Award from the National Institutes of Health.

Part I: Molecular Components of Cells

1. The Facts of Life: Chemistry Is the Logic of Biological Phenomena

2. Water: The Medium of Life

3. Thermodynamics of Biological Systems

4. Amino Acids and the Peptide Bond

5. Proteins: Their Primary Structure and Biological Functions

6. Proteins: Secondary, Tertiary, and Quaternary Structure

7. Carbohydrates and the Glycoconjugates of Cell Surfaces

8. Lipids

9. Membranes and Membrane Transport

10. Nucleotides and Nucleic Acids

11. Structure of Nucleic Acids

12. Recombinant DNA, Cloning, Chimeric Genes, and Synthetic Biology

Part II: Protein Dynamics

13. Enzymes—Kinetics and Specificity

14. Mechanisms of Enzyme Action

15. Enzyme Regulation

16. Molecular Motors

Part III: Metabolism and Its Regulation

17. Metabolism: An Overview

18. Glycolysis

19. The Tricarboxylic Acid Cycle

20. Electron Transport and Oxidative Phosphorylation

21. Photosynthesis

22. Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway

23. Fatty Acid Catabolism

24. Lipid Biosynthesis

25. Nitrogen Acquisition and Amino Acid Metabolism

26. Synthesis and Degradation of Nucleotides

27. Metabolic Integration and Organ Specialization

Part IV: Information Transfer

28. DNA Metabolism: Replication, Recombination, and Repair

29. Transcription and the Regulation of Gene Expression

30. Protein Synthesis

31. Completing the Protein Life Cycle: Folding, Processing, and Degradation

32. The Reception and Transmission of Extracellular Information

Abbreviated Answers to Problems

Index

ISBN: 9781305577206
ISBN-10: 1305577205
Audience: Tertiary; University or College
Format: Hardcover
Language: English
Number Of Pages: 1280
Published: 1st January 2016
Publisher: Cengage Learning, Inc
Country of Publication: US
Dimensions (cm): 28.4 x 23.6  x 5.0
Weight (kg): 2.72
Edition Number: 6
Edition Type: Revised

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