Remarkable progress has occurred over the past 30 years in the study of zinc metabolism in humans, as researchers continue to investigate zinc's important nutritional and immunological roles in the body. Zinc deficiency has been linked to numerous immune deficiency disorders and to growth retardation in children and adolescents. In addition, zinc has proven to be an effective therapy for Wilson's disease and the once fatal acrodermatitis enteropathica.
Biochemistry of Zinc critically examines these and other significant advances in basic research and relates them to the biological results of insufficient amounts of zinc in the body. This comprehensive text describes several recently discovered effects of zinc deficiency - such as anergy, and decreased levels of IL-2 and IL-1 production, natural killer cell activity, and active thymulin peptide - and assesses their clinical implications in the treatment of zinc-related immune disorders. It covers all the vital biochemical information on zinc and its functions, including its interactions with enzymes, hormones, lipid metabolism, cells, neurobiology, and other micronutrients. The book also discusses the relevant historical aspects of zinc and features an informative chapter on techniques for measuring zinc in biological samples, using atomic absorption spectrophotometry.
Providing a solid foundation for future research, Biochemistry of Zinc is a thorough, state-of-the-art resource for researchers and students in biochemistry, nutrition, and medical research, as well as physicians who are likely to encounter zinc-related problems in their practice.
|Historical Aspects of Zinc||p. 1|
|Zinc and Enzymes||p. 17|
|Zinc and Gene Expression||p. 55|
|Biochemistry of Metallothionein||p. 77|
|Zinc and Hormones||p. 93|
|Zinc and Lipid Metabolism||p. 119|
|Zinc and Cells||p. 131|
|Zinc and Neurobiology||p. 149|
|Zinc and Immunity||p. 165|
|Metabolism of Zinc||p. 193|
|Clinical Spectrum of Human Zinc Deficiency||p. 219|
|Interactions of Zinc with Other Micronutrients||p. 259|
|Techniques for Measurement of Zinc in Biological Samples||p. 279|
|Table of Contents provided by Blackwell. All Rights Reserved.|
Series: Biochemistry of the Elements
Number Of Pages: 303
Published: 31st January 1994
Publisher: Springer Science+Business Media
Country of Publication: US
Dimensions (cm): 22.9 x 15.2 x 3.18
Weight (kg): 1.39