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Basic Mutagenicity Tests : UKEMS Recommended Procedures - David J. Kirkland

Basic Mutagenicity Tests

UKEMS Recommended Procedures

By: David J. Kirkland (Editor)

Hardcover Published: 5th June 2004
ISBN: 9780521393478
Number Of Pages: 160

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This volume provides a brief but important summary of the essential tests that need to be performed on all new compounds--whether they are new drugs, pesticides or food additives--before they can be registered for use in the United Kingdom. These basic tests for mutagenicity, originally drawn up by the United Kingdom Environmental Mutagen Society in 1983 have now been fully revised under the auspices of expert working groups from academia and industry and in collaboration with the UK Department of Health. This volume therefore provides the latest official guidelines and recommendations for all scientists involved in the testing and registration of new compounds not only in the UK, but in wider international context. The four main test procedures for measuring mutagenicity described in this volume are bacterial mutation assays, metaphase chromosome aberration assays in vitro, gene mutation assays in cultured mammalian cells, and in vivo cytogenetics assays. Each of these tests is fully explained and described in practical and procedural detail, with additional information on the presentation and data processing of results.

Steering group
List of abbreviations
Bacterial mutation assays
Metaphase chromosome aberration assays in vitro
Gene mutation assays in cultured mammalian cells
In vivo cytogenetics assays
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9780521393478
ISBN-10: 0521393477
Series: Ukems Sub-Committee on Guidelines for Mutagenicity Testing. Report. Part I Revised : Book 1
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 160
Published: 5th June 2004
Country of Publication: GB
Dimensions (cm): 22.86 x 15.24  x 1.27
Weight (kg): 0.41