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Apoptosis and It's Modulation by Drugs : Handbook of Experimental Pharmacology - Ross G. Cameron

Apoptosis and It's Modulation by Drugs

Handbook of Experimental Pharmacology

By: Ross G. Cameron (Editor), George Feuer (Editor)

Hardcover Published: February 2000
ISBN: 9783540661214
Number Of Pages: 478

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This book is concernced with the process of cell death in human cells by programmed cell death or apoptosis, and the modulation of this process by drugs. This is a new field of study and this volume represents the first comprehensive treatment of this subject matter. Its focus is on human biology and medicine. Apoptosis is a very prevalent type of cell death with importance in human diseases such as cancer, Alzheimer's disease and autoimmune disorders. The book combines the expertise of leading scientists and writers from fields as diverse as neurosciences, immunology, pathology and cancer research. There is detailed analysis of the molecular and cellular aspects of apoptosis including the specific genes and molecules involved in the regulation of this special form of programmed cell death. Scientists, clinicians and researchers involved in studies of human biology and medicine will find this book an excellent resource.

Incidence of Apoptosis and Its Pathological and Biochemical Manifestationsp. 1
Molecular Cellular and Tissue Reactions of Apoptosis and Their Modulation by Drugsp. 37
Hepatocyte Apoptosis Triggered by Natural Substances (Cytokines, Other Endogenous Molecules and Foreign Toxins)p. 59
The Role of C-type Protein Kinases in Apoptosisp. 109
How Does Programmed Cell Death Contribute to AIDS Pathogenesis?p. 127
Apoptotic Cell Phagocytosisp. 151
T Cell Apoptosis and Its Role in Peripheral Tolerancep. 179
Apoptosis of Nerve Cellsp. 197
Use of p53 as Cancer Cell Target for Gene Therapyp. 235
Antioxidants: Protection Versus Apoptosisp. 257
Reactive Oxygen Species and Apoptosisp. 275
Clearance of Apoptotic Lymphocytes by Human Kupffer Cells. Phagocytosis of Apoptotic Cells in the Liver: Role of Lectin Receptors, and Therapeutic Advantagesp. 319
Drug-Induced Apoptosis of Skin Cells and Liverp. 343
Apoptosis and Eosinophilsp. 357
Thymocyte and B-Cell Death Without DNA Fragmentationp. 375
Antigen Receptor-Induced Death of Mature B Lymphocytesp. 399
Modulation of Apoptosis and Maturation of the B-Cell Immune Responsep. 429
The Neuroprotective and Neuronal Rescue Effect of (-)-Deprenylp. 457
Subject Indexp. 473
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9783540661214
ISBN-10: 3540661212
Series: Handbook of Experimental Pharmacology
Audience: General
Format: Hardcover
Language: English
Number Of Pages: 478
Published: February 2000
Publisher: Springer-Verlag Berlin and Heidelberg Gmbh & Co. Kg
Country of Publication: DE
Dimensions (cm): 23.39 x 15.6  x 2.87
Weight (kg): 0.89

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