Antigen and Antibody Molecular Engineering in Breast Cancer Diagnosis and Treatment : Diagnosis and Treatment

By: Roberto L. Ceriani (Editor)

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240 Pages

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25.4 x 17.78 x 1.42

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The 1992 session of the biennial workshop concerned with the immunology of breast cancer focused on the recent advances in understanding the molecular biology both of antigens associated with breast cancer and of their corresponding antibodies. Among the topics of the 19 papers are peptide epitopes

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Non-Fiction Medicine Clinical & Internal Medicine Diseases & Disorders Oncology Immunology Science Biology, Life Sciences Biochemistry Engineering & Technology Biochemical Engineering Biotechnology

Breast Mucin and Associated Antigens in Diagnosis and Therapy	p. 1
Peptide Epitopes in Breast Cancer Mucins	p. 9
Does a Novel Form of the Breast Cancer Marker Protein, MUC1, Act as a Receptor Molecule that Modulates Signal Transduction?	p. 17
Cancer Metastasis Determined by Carbohydrate-Mediated Cell Adhesion	p. 27
Experimental Immunotherapy of Breast Cancer Using Alpha Interferon Conjugated to Monoclonal Antibody Mc5	p. 35
Circulating and Tissue Markers in the Longitudinal Management of Breast Cancer Patients	p. 47
Engineering of Antibodies for Breast Cancer Therapy: Construction of Chimeric and Humanized Versions of the Murine Monoclonal Antibody BrE-3	p. 55
Humanization of an Anti-Mucin Antibody for Breast and Ovarian Cancer Therapy	p. 61
Towards an Immunotherapy for p185[superscript HER2] Overexpressing Tumors	p. 83
Branching N-Linked Oligosaccharides in Breast Cancer	p. 95
Specificity of the IgG Response in Mice and Human Breast Cancer Patients Following Immunization Against Synthetic Sialyl-Tn, an Epitope with Possible Functional Significance in Metastasis	p. 105
Vaccination Against Breast Cancer - Studies in an Animal Model	p. 125
Anti-Idiotype Antibodies as Potential Therapeutic Agents for Human Breast Cancer	p. 139
The Simultaneous Expression of c-erbB-2 Oncoprotein and Laminin Receptor on Primary Breast Tumors has a Predicting Potential Analogous to that of the Lymph Node Status	p. 149
Multivariate Prognostic Model for Infiltrating Ductal Carcinoma of the Breast in the Axillary Node-Free Patient	p. 155
The Use of Monoclonal Antibody Immunoconjugates in Cancer Therapy	p. 169
Radioimmunolocalization of Breast Cancer Using BrE-3 Monoclonal Antibody	p. 181
Suppression of Human Anti-Mouse Antibody Response to Murine Monoclonal Antibody L6 by Deoxyspergualin: A Phase I Study	p. 193
Overview of Radioimmunotherapy in Advanced Breast Cancer Using I-131 Chimeric L6	p. 203
Contributors	p. 213
Index	p. 219
Table of Contents provided by Blackwell. All Rights Reserved.

Antigen and Antibody Molecular Engineering in Breast Cancer Diagnosis and Treatment : Diagnosis and Treatment

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Hardcover

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