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Animal Cells as Bioreactors : Cambridge Studies in Biotechnology - Terence Cartwright

Animal Cells as Bioreactors

Cambridge Studies in Biotechnology

Hardcover Published: 26th August 1994
ISBN: 9780521412582
Number Of Pages: 196

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This book covers all aspects of the new technologies needed to turn animal cells into an acceptable and cost-effective tool for drug production. This includes modifying them genetically so that they produce the right product in high yield, getting them to grow reproducibly on an industrial scale, and extracting the required product from them. It also covers biological safety issues, and the verification of the chemical and biological nature of the protein drug produced. The work covers the latest developments in all of these areas and how they all need to be integrated for the design of an effective biotechnological production process.

' ... provides a useful reference work for all budding biotechnologists.' Wendie Norris, British Society for Development Biology Newsletter

Introducing the animal cell as a bioreactor
Yield of recombinant product: engineering cells for maximum expression
The generation of biomass, medium design for animal cell culture, fermenter design for animal cell culture, suspension cultures, immobilized cells, process control
Adjusting cellular metabolism for optimum product yield
Downstream processing
Regulatory aspects of using cells as bioreactors, viral contamination of animal cell derived pharmaceuticals
Overview and conclusions
References
Index
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9780521412582
ISBN-10: 0521412587
Series: Cambridge Studies in Biotechnology
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 196
Published: 26th August 1994
Publisher: Cambridge University Press
Country of Publication: GB
Dimensions (cm): 22.8 x 15.2  x 1.4
Weight (kg): 0.46