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Animal Cell Technology: Basic & Applied Aspects : Proceedings of the Fifteenth Annual Meeting of the Japanese Association for Animal Cell Technology (JAACT), Fuchu, Japan, November 11-15, 2002 - Kazumi Yagasaki

Animal Cell Technology: Basic & Applied Aspects

Proceedings of the Fifteenth Annual Meeting of the Japanese Association for Animal Cell Technology (JAACT), Fuchu, Japan, November 11-15, 2002

By: Kazumi Yagasaki (Editor), Yutaka Miura (Editor), Makoto Hatori (Editor), Yoshihiro Nomura (Editor)

Hardcover Published: 19th May 2004
ISBN: 9781402019708
Number Of Pages: 518

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Animal cell technology is a growing discipline of cell biology which aims not only to understand structures, functions and behaviors of differentiated animal cells, but also to ascertain their abilities to be used in industrial and medical purposes. The goal of animal cell technology includes accomplishments of clonal expansion of differentiated cells with useful ability, optimization of their culture conditions, modulation of their ability for production of medically and pharmaceutically important proteins and the application of animal cells to gene therapy, artificial organs and functional foods. This volume gives the readers a complete review of present state-of-the-art in Japan and other countries where this field is well advanced. The Proceedings will be useful for the cell biologists, biochemists, molecular biologists, immunologists, biochemical engineers and other disciplines related to animal cell culture, working in either academic environments or in industries of biotechnology and pharmacy. 'Skeletal metastases are both a common and devastating consequence of a spectrum of cancers. Significant advances have occurred in our understanding of the pathobiology of this process

Recombinant expression of human collagensp. 1
Expression profiling of parietal endoderm cells and development of systems for large scale production of lamininsp. 7
Synthetic peptides from laminin for tissue engineeringp. 13
A novel technology for conversion of in vivo tissue architecture into a three-dimensional in vitro culture modep. 19
Construction of liver model with genetically engineered human HepG2 cellsp. 25
Determinants of ligand specificity in group I and IV WW domainsp. 31
Role of the WW domain in signaling and diseasep. 37
Structural biology of signal transduction mediated by Grb2p. 43
Modulation of leukocyte function by food factorsp. 49
Anticancer effects of lignansp. 55
Effect of sulfur-containing active principles in garlic on the physiological function of hepatocytesp. 59
Suppression of free radical-induced mutation of animal cell genes by food factorsp. 65
Chemoenzymatic approaches for the preparation of oligosaccharides and glycopeptidesp. 71
Cell growth arrest by nucleotides as a tool for improved production of biopharmaceuticalsp. 77
Transient gene expression : a novel mammalian cell-based technology for recombinant protein productionp. 83
Optimization of the production of retroviral vectors : influences of the sugar sourcep. 89
Effects of glucose and CO[subscript 2] concentrations on CHO cell physiologyp. 99
Suppression of glutamate-induced neural cell death by electrolyzed-reduced waterp. 105
Development of apoptosis-resistant dihydrofolate reductase-defficient Chinese hamster ovary cell linep. 111
High expression of human monoclonal antibodies in CHO cells selected using a cycloheximide resistance markerp. 117
Development of a serum-free medium supplemented with hydrolysate for the suspension culture of recombinant CHO cells producing human thrombopoietinp. 121
Effect of growth factors and ascorbic acid 2-phosphate on liver specific functions of porcine hepatocytesp. 127
Culture of porcine hepatocytes using radial flow bioreactor systemp. 133
The role of glutamine in hybridoma cell culturep. 139
Protective action of reduced water against alloxan-induced cytotoxicity in pancreatic [beta]-cellp. 145
Effect of doxycycline-regulated chaperone expression on recombinant protein productivity in CHO cellsp. 151
Biphasic culture strategy based on hyperosmotic pressure for improved humanized antibody production in Chinese hamster ovary cell culturep. 157
Effect of low culture temperature on foreign protein production in recombinant CHO cellsp. 163
Control of temperature and pH enhances human monoclonal antibody production in CHO cell culturep. 169
Effects of pluronic F68 on t-PA producing Chinese hamster ovary (CHO) cells under agitating and static conditionsp. 173
Structure and function of laminin [alpha]4 G domainp. 179
Introduction of apoptosis-resistant genes of hybridoma cells and their influencep. 185
An engineering method to high yielding production of recombinant anti-HIV monoclonal antibody using generic multi feed fermentationp. 191
Proliferation and monoclonal antibody production of hybridoma cells immobilized on non-woven polyester fabric discsp. 197
Mass-production in yeast of laminins as the material of reconstructive therapyp. 203
Effects of carvacrol on a human non-small cell lung cancer (NSCLC) cell line, A549p. 207
Establishment of dendritic cell line from caspase-1-defficient micep. 213
Isolation and characterization of fetal bovine cells derived from liver and bone marrowp. 219
Artificial selection of high proliferating and apoptosis-resistant NS0 cells for industrial production systemp. 225
Endothelial cells culture and its use to produce a vaccine against rickettsiaep. 233
Monocytes suppress immune responses of peripheral blood lymphocytes : possible implication of immature dendritic cellsp. 237
Establishment and analysis of germfee T cell receptor transgenic micep. 243
Development of a novel process to produce a veterinary rabies vaccine in BHK-21 cells grown on microcarriers in a 20 liter bioreactorp. 249
Epitope-specific suppression of immune response against [beta]-lactoglobulin induced by oral administration of cow's milk with heat treatmentsp. 255
Production of anti-peptide antibody by in vitro immunizationp. 261
Generation of mouse-human hybridomas secreting antibodies against peanut allergensp. 267
Reduced immunogenicity of [beta]-lactoglobulin by conjugation with alginic acid oligosaccharidep. 273
Evaluation of the immuno-protective effect of the new-type of bags using ELISA-and FACS-analysisp. 277
Effect of silk protein sericin on hepatoblastoma HepG2 cellsp. 281
Isolation of human mesenchymal stem cell-like fibroblast from adipose tissue for reconstructive therapyp. 287
Change of the cellular function by connexin gene transfection in a hepatoma cell linep. 293
Production of pharmaceutical proteins by transgenic avianp. 299
Influence of serum concentration on cell growth and retrovirus production and decay kineticsp. 305
Neural precursor cells from adult mouse cerebral cortexp. 311
The inhibition of MMP-2 expression in human fibrosarcoma HT1080 cells by electrolyzed-reduced waterp. 317
The role of plasminogen in the proliferation of murine hepatocytes in primary culturep. 323
Transcriptional regulation mechanisms of telomerase reverse transcriptase gene responsible for ubiquitous expression of telomerase in mousep. 329
Cell proliferation switch responsive to fluorescein dimerp. 335
Hydrogen peroxide triggers cellular senescence programs : possible application to tumor suppressionp. 341
Essential role of cell-cell interaction in primary hepatocyte culturesp. 347
Involvement of myosin light chain in suppressive effect of epigallocatechin-3-O-gallate on histamine release from the human basophilic KU812 cellsp. 353
Proteomic analysis of changes in excitable and non-excitable cells exposed to DC electric fields of physiological strengthp. 359
Inhibition of the expression of IgE heavy chain germline transcripts by peroxisome proliferator-activated receptor-[gamma] ligandsp. 363
Negative regulation of the basophil activation by natural ligands for peroxisome proliferator-activated receptorsp. 369
Two-dimensional electrophoresis of proteins from human intestinal Caco-2 cells exposed to the known xenoestrogen nonylphenolp. 375
The suppressive effect of electorolyzed reduced water on lipid peroxidationp. 381
Electrolyzed reduced water induces differentiation in K-562 human leukemia cellsp. 387
Oral administration of soy isoflavones and determination of serum isoflavone levels in Sprague-Dawley ratsp. 393
Effect of [beta]-casein on cytokine production of mouse spleen lymphocytesp. 399
Changes in the relevant test paramaetrs of 219 diabetes patients under the influence of the so called "Nordenau - phenomenon" in the prospective observation procedurep. 405
Decreased intracellular peroxide levels of rat ascites hepatoma cells by resveratrol and sera from resveratrol-treated ratsp. 411
Inhibitory effects of several flavonoids on prostaglandin production and E-selectin expression in cultured animal cellsp. 417
Phytoestrogens enhance the acetylcholinesterase activity of the rat pheochromocytoma cell line PC12 by binding to the estrogen receptorp. 423
Sericin protein derived from silk accelerated proliferation of mammalian cellsp. 429
Effect of the administration of shark type-I collagen to ovariectomized ratsp. 435
Alginic acid oligosaccharide up-regulates IFN-[gamma] production by lymph node cellsp. 441
Actions of sulfur amino acids on lipase activities in cultured adipocytesp. 447
Analysis of the mechanism of the tight-junctional permeability increase by capsaicin treatment on the intestinal Caco-2 cellsp. 453
Effect of shark skin collagen on morphologic and biochemical changes in a guinea pig model of osteoarthritisp. 459
Inhibitory effect of conjugated linoleic acid isomers on the proliferation of human breast cancer cellsp. 465
Effects of carvacrol on sister chromatid exchanges in human lymphocyte culturesp. 471
Biocompatible biomaterials for the human chondrocyte differention estimated by RT-PCR methodp. 475
Different expression of gap junctional protein connexin 43 in two strains of mice after one-month implantation of poly-L-lactic acidp. 481
Changes on cell surface and microfilament distribution during myoblast differentiation and transformation in vitrop. 487
Primary cilium in CO25 cell linep. 493
Environmental chemicals affect nerve cell differentiation in SFME cells through specific gene expressionp. 499
Evaluation of the cornea cells affects by multi-purpose solutions for contact-lensp. 505
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9781402019708
ISBN-10: 140201970X
Series: Animal Cell Technology: Basic & Applied Aspects : Book 13
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 518
Published: 19th May 2004
Publisher: Springer-Verlag New York Inc.
Country of Publication: US
Dimensions (cm): 29.7 x 21.0  x 2.54
Weight (kg): 2.04