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Alzheimer's Disease and Other Dementias : A Clinician's Guide to Diagnosis and Management - Richard Caselli

Alzheimer's Disease and Other Dementias

A Clinician's Guide to Diagnosis and Management


Published: 10th October 2010
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The number of patients with dementia is rising in proportion to the aging of our population; therefore, by 2050 the prevalence of Alzheimer's disease is expected to triple, risking the integrity of the entire U.S. healthcare economy. More NIH dollars are spent on Alzheimer's disease research than on any other neurological disease and our available fund of information has commensurately accelerated. Whereas 30 years ago little distinction was made between different forms of dementia, clinicians now distinguish multiple degenerative and vascular syndromes, each with their own etiologic, therapeutic and prognostic implications. New genetic insights reach the popular press on a regular basis. Consequently Alzheimer's disease (and related disorders) has become a special concern to the majority of the population whose main avenue of care lies with the primary care physician.
The primary care physician (general internist, family practitioner, nurse practitioner), geriatrician, and geriatric psychiatrist are the target audiences for this book; in short anyone who is not a neurological expert who provides dementia-related care. As the primary care physician is the target audience for this title, the volume begins with a discusion of how to produce an effective diagnosis through a series of precise, easy- to- follow steps. Additional sections detail the current research state of each of the major individual dementia diseases that the general clinician frequently encounters. The last section procides a clinically focused 'how to' guide for treatment including symptom-directed pharmacotherapy, as well as an up-to-date summary of ongoing major therapeutic trials and an assessment non-pharmacological management issues such as driving and end-of- life considerations. Aiming to be clear, consice and practical, this volume provides the essential information in dementia related care, from disease diagnosis to symptom management. Because it uses the most up-to-date dementia research available, this volume will become a close companion of the primary care physician, who seeks direct answers to the common questions and issues that arise in the diagnosis and management of patients with dementia.

"Dr. Caselli and Tariot provide the primary care provider a unique perspective on Alzheimer's disease in this their first collaborative publication. It is organized as one might think through the process of caring for a patient and they have to link structure to function throughout the manual. For those who wish a deeper understanding of Alzheimer's disease and see a high proportion of elderly patients, this book will take you to new levels of understanding without bogging down. Case vignettes will keep your interest throughout almost every chapter." Eric G. Tangalos, MD; Professor of Medicine and Chair, Emeritus, Primary Care Internal Medicine, Mayo Clinic College of Medicine "This book is a practical guide to the diagnosis, management and treatment of Alzheimer's disease and related disorders which is comprehensive, comprehensible as well as scientifically accurate. It is a pleasure to read and will be useful to all involved in the dealing with the epidemic of dementia in developed countries." John Hardy PhD, MD (Hon), FMedSci., FRS., Department of Molecular Neuroscience and Reta Lilla Weston Laboratories Institute of Neurology, London

Section A: The Diagnosis and Evaluation of Dementia Chapter 1. Normal Aging and Memory Decline Chapter 2. Characterizing a Cognitive Disorder Chapter 3. Diagnostic Evaluation of Suspected Alzheimer's Disease Chapter 4. When It's Not Alzheimer's Disease: Four Brief Illustrative Cases of Reversible "Dementias"

Section B: Alzheimer's Disease and Its Clinical Syndromes Chapter 5. The Neurobiology of Alzheimer's Disease Chapter 6. The Classic Clinical Syndromes of Alzheimer's Disease Chapter 7. Clinical Variants of Alzheimer's Disease Chapter 8. Neuropathological Overlap Syndromes

Section C: Pharmacotherapy of Alzheimer's Disease (And Other Forms of Demenetia): A Practical Approach to Medical Management Chapter 9: Pharmacotherapy: Cognitive Impairment Chapter 10: Pharmacotherapy: Behavioral Problems Chapter 11: Pharmacotherapy: Other Issues

Section D: Nonpharmacological Management Chapter 12. Acute Interventions Chapter 13. Communicating With Dementia Patients Chapter 14. Managing Problem Behaviors, Aggression, and Violence Chapter 15. Planning Ahead: Legal Issues and Advance Directives Chapter 16. The Long Term Care Continuum Chapter 17. End of Life Care for Dementia Chapter 18. Caring For the Caregiver

Section E. Experimental and Future Therapies Chapter 19. Neurotransmitter-Based Interventions Chapter 20. Amyloid-Based Interventions Chapter 21. Tau-Based Interventions Chapter 22. Other Agents

ISBN: 9780195393385
ISBN-10: 0195393384
Series: Oxford American Neurology Library
Audience: General
Format: Paperback
Language: English
Number Of Pages: 264
Published: 10th October 2010
Country of Publication: US
Dimensions (cm): 20.32 x 12.7  x 1.4
Weight (kg): 0.26