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Advances in Inflammatory Bowel Diseases : Falk Symposium - P. Rutgeerts

Advances in Inflammatory Bowel Diseases

Falk Symposium

By: P. Rutgeerts (Editor), J. F. Colombel (Editor), S. B. Hanauer (Editor), J. Scholmerich (Editor), G. N. Tytgat (Editor)

Hardcover Published: 31st December 1998
ISBN: 9780792387503
Number Of Pages: 320

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Ulcerative colitis and Crohn's disease remain a great therapeutic challenge to the medical community. In recent years knowledge about the pathogenesis of these diseases has progressed rapidly but the cause of the diseases remains completely unknown. It has become clear that dysregulation of the mucosal immune system is the basis for the chronic evolution of the diseases in a genetically susceptible population. Exciting new therapeutic approaches have been attempted in the last couple of years and cytokine and anti-cytokine treatments in particular seem very promising, especially in intractable disease. The format of the Falk Symposium 106 on Advances in Inflammatory Bowel Diseases', held in Brussels, Belgium, June 18-20, 1998, was somewhat innovative as each session attempted to link the new insights into pathogenetic mechanisms with new therapeutic approaches, resulting in optimal information transfer. The classic therapeutic schemes were updated with a special focus on step-wise build-up of therapy.

List of Principal Authorsp. viii
Prefacep. xi
Aetiological Factors in Ibd
Susceptibility genes in inflammatory bowel diseasesp. 3
Genetic heterogeneity within inflammatory bowel diseasep. 17
Inflammatory bowel disease and genetics: What to tell our patients?p. 24
The importance of environment in inflammatory bowel disease: New datap. 34
Nicotine in the treatment of ulcerative colitisp. 43
Pathogenesis of Ibd
Inflammatory lesions of the myenteric plexus in Crohn's diseasep. 55
The infectious track in inflammatory bowel diseasesp. 68
The role of nutrition in the pathogenesis of inflammatory bowel diseasep. 80
Role of nutritional therapy in IBDp. 89
Immunological Basis of Ibd
Animal models of IBD: Impact on understanding immunologically mediated intestinal inflammationp. 105
The role of IFN-[gamma] in inflammation and immunopathologyp. 112
The role of interleukin-12 in inflammatory bowel diseasep. 130
Cytokines and inflammatory bowel diseasep. 135
Immunomodulation therapy in inflammatory bowel diseases: Cytokines and anti-cytokinesp. 145
Cancer in Ibd
Risk factors for development of colorectal cancer in inflammatory bowel diseasep. 159
Early detection of cancer in inflammatory bowel disease: What should be done?p. 168
Utility of IBD classification: Is it helpful from a therapeutic standpoint?p. 185
Aetiopathogenesis of IBD: Where do we stand?p. 188
Standard Therapies in IBD
Aminosalicylates in the treatment of ulcerative colitis and Crohn's diseasep. 201
How to use steroids in inflammatory bowel diseasep. 210
Immunosuppression therapy in ulcerative colitis and Crohn's diseasep. 218
Sequential therapy for inflammatory bowel diseasep. 227
Surgery for IBD
Surgery for Crohn's disease: When to operate, how to operatep. 233
Natural history of Crohn's recurrence at the ileocolonic anastomosisp. 244
Relapse prevention strategies in Crohn's diseasep. 251
Changes in prognosis for patients with inflammatory bowel diseasep. 257
IBD: a Systemic Disease
Trefoil peptides and inflammatory bowel diseasep. 269
Functional neuroimmune interactions in IBD and their therapeutic implicationsp. 275
Inflammatory arthropathy and inflammatory bowel diseasep. 280
Refractory anaemia and iron deficiency in IBDp. 288
Manipulation of intestinal microflorap. 297
Pathogenesis and treatment of pouchitisp. 301
Indexp. 311
Table of Contents provided by Syndetics. All Rights Reserved.

ISBN: 9780792387503
ISBN-10: 0792387503
Series: Falk Symposium
Audience: General
Format: Hardcover
Language: English
Number Of Pages: 320
Published: 31st December 1998
Publisher: Springer
Country of Publication: NL
Dimensions (cm): 23.39 x 15.6  x 1.91
Weight (kg): 0.64