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Advances in Genetics Volume 48 : Volume 48 - Jeffrey Hall

Advances in Genetics Volume 48

Volume 48

Hardcover Published: 7th February 2003
ISBN: 9780120176489
Number Of Pages: 286

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Biological rhythms, such as the sleep-wake cycle or circadian clock, are an intriguing aspect of biology. The regulation of daily rhythmicity has long been a mystery, up until the mid-1980's when a key gene in the fruitfly, "Drosophila melanogaster," was molecularly identified. Genetic and molecular chronobiology of "Drosophila" has been a driving force in this field of inquiry ever since. This book describes and evaluates all of the studies of this sort, discussing the manner by which these investigations have spread out in various directions of rhythmic biology, including genetic and molecular approaches used on other insect species.
* Discusses rhythm genetics in insects, from early investigations to current state-of-the-art
* Presents all relevant mutants and genes
* Highlights the mystery of the "clock mechanism" in full detail including the remaining puzzles to be solved

Genetics and Molecular Biology of Rhythms in Drosophila and Other Insectsp. 1
Introductionp. 4
Mutants Used to Identify Cells and Tissues that Mediate Inputs to Circadian Pacemakers in Drosophilap. 6
Mutants Apparently Defective in Central-Pacemaking Functions Underlying Drosophila's Circadian Rhythmicityp. 13
Additional Mutants with Defects in Daily Cycles and Other Time-Based Phenotypesp. 34
Molecular Genetics of Central-Pacemaking Functionsp. 72
Places and Times of Clock-Gene Expressionsp. 113
Natural Variants of Clock Genes, Including Interspecific Studiesp. 140
Temperature Changes and How Clock-Gene Products are Involved in Compensating for Themp. 161
Molecular Genetics of Clock Resetting by Environmental Stimulip. 167
Gene-Defined Functions Connecting Central Pacemaking to Circadian Chronobiologyp. 193
Conclusionp. 232
Referencesp. 233
Glossaryp. 258
Indexp. 281
Table of Contents provided by Syndetics. All Rights Reserved.

ISBN: 9780120176489
ISBN-10: 0120176483
Series: Advances in Genetics
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 286
Published: 7th February 2003
Publisher: Elsevier Science Publishing Co Inc
Country of Publication: US
Dimensions (cm): 22.9 x 15.2  x 1.91
Weight (kg): 0.52

Earn 305 Qantas Points
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