| Membrane Ectopeptidases with Influence on Immune Functions | |
| Review: The Role of Membrane Peptidases in Immune Functions | p. 1 |
| Structure and Function of Aminopeptidase N | p. 25 |
| Modulation of WNT-5a Expression by Actinonin: Linkage of APN to the WNT-Pathway? | p. 35 |
| Enzymatic Activity is not a Precondition for the Intracellular Calcium Increase Mediated by mAbs Specific for Aminopeptidase N/CD13 | p. 43 |
| Transforming Growth Factor-[beta] Increases the Expression of Aminopeptidase N/CD13 mRNA and Protein in Monocytes and Monocytic Cell Lines | p. 49 |
| Cell-Cell Contact Between Lymphocytes and Fibroblast-like Synoviocytes Induces Lymphocytic Expression of Aminopeptidase N/CD13 and Results in Lymphocytic Activation | p. 57 |
| Natural Substrates of Dipeptidyl Peptidase IV | p. 67 |
| Relating Structure to Function in the Beta-Propeller Domain of Dipeptidyl Peptidase IV: Point Mutations that Influence Adenosine Deaminase Binding, Antibody Binding and Enzyme Activity | p. 89 |
| Development of a Tertiary-Structure Model of the C-Terminal Domain of DPP IV | p. 97 |
| Post Proline Cleaving Peptidases Having DP IV Like Enzyme Activity: Post-Proline Peptidases | p. 103 |
| A New Type of Fluorogenic Substrates for Determination of Cellular Dipeptidyl Peptidase IV (DP IV/CD26) Activity | p. 111 |
| Potent Inhibitors of Dipeptidyl Peptidase IV and their Mechanisms of Inhibition | p. 117 |
| N-terminal HIV-1 TAT Nonapeptides as Inhibitors of Dipeptidyl Peptidase IV. Conformational Characterization | p. 125 |
| Signal Transduction Events Induced or Affected by Inhibition of the Catalytic Activity of Dipeptidyl Peptidase IV (DP IV, CD26) | p. 131 |
| Specific Inhibitors of Dipeptidyl Peptidase IV Suppress mRNA Expression of DP IV/CD26 and Cytokines | p. 139 |
| Dipeptidyl Peptidase IV in Inflammatory CNS Disease | p. 145 |
| Dipeptidyl Peptidase IV (CD26): Role in T Cell Activation and Autoimmune Disease | p. 155 |
| Effects of Nonapeptides Derived from the N-Terminal Structure of Human Immunodeficiency Virus-1 (HIV-1) TAT on Suppression of CD26-Dependent T Cell Growth | p. 161 |
| DNA Synthesis in Cultured Human Keratinocytes and HACAT Keratinocytes is Reduced by Specific Inhibition of Dipeptidyl Peptidase IV (CD26) Enzymatic Activity | p. 167 |
| Attractin: A CUB-Family Protease Involved in T Cell-Monocyte/Macrophage Interactions | p. 173 |
| Analogs of Glucose-Dependent Insulinotropic Polypeptide with Increased Dipeptidyl Peptidase IV Resistance | p. 187 |
| Dipeptidyl Peptidase IV (DPP IV, CD26) in Patients with Mental Eating Disorders | p. 197 |
| The Membrane-Bound Ectopeptidase CPM as a Marker of Macrophage Maturation in Vitro and in Vivo | p. 205 |
| Matrix Metalloproteinases (MMP-8, -13, and -14) Interact with the Clotting System and Degrade Fibrinogen and Factor XII (Hagemann Factor) | p. 217 |
| The Neprilysin Family in Health and Disease | p. 229 |
| Cellular Endopeptidases: New Cathepsins; Results from Knock-out-mice; Regulatory Aspects | |
| Review: Novel Cysteine Proteases of the Papain Family | p. 241 |
| Development and Validation of Homology Models of Human Cathepsins K, S, H, and F | p. 255 |
| The Function of Propeptide Domains of Cysteine Proteinases | p. 261 |
| Human Cathepsins W and F Form a New Subgroup of Cathepsins that is Evolutionarily Separated from the Cathepsin B- and L-like Cysteine Proteases | p. 271 |
| Cathepsin K Expression in Human Lung | p. 281 |
| Expression of Cathepsins B and L in Human Lung Epithelial Cells is Regulated by Cytokines | p. 287 |
| Functions of Cathepsin K in Bone Resorption: Lessons from Cathepsin K Deficient Mice | p. 293 |
| Ceramide as an Activator Lipid of Cathepsin D | p. 305 |
| Human Cathepsin X: A Novel Cysteine Protease with Unique Specificity | p. 317 |
| A Novel Proteolytic Mechanism for Termination of the Ca[superscript 2+] Signalling Evoked by Proteinase-Activated Receptor-1 (PAR-1) in Rat Astrocytes | p. 323 |
| Natural and Synthetic Inhibitors of the Tumor-Associated Serine Protease Urokinase-Type Plasminogen Activator | p. 331 |
| Processing of Interleukin-18 by Human Vascular Smooth Muscle Cells | p. 343 |
| Peptidases and Peptidase Inhibitors in Pathogenesis of Diseases | |
| Review: Peptidases and Peptidase Inhibitors in the Pathogenesis of Diseases: Disturbances in the Ubiquitin-Mediated Proteolytic System. Protease-Antiprotease Imbalance in Inflammatory Reactions. Role of Cathepsins in Tumour Progression | p. 349 |
| The Role of Proteolysis in Alzheimer's Disease | p. 379 |
| Observing Proteases in Living Cells | p. 391 |
| The Role of Cysteine Proteases in Intracellular Pancreatic Serine Protease Activation | p. 403 |
| Peptidases in the Asthmatic Airways | p. 413 |
| Inactivation of Interleukin-6 by Neutrophil Proteases at Sites of Inflammation: Protective Effects of Soluble IL-6 Receptor Chains | p. 431 |
| Antisense Inhibition of Cathepsin B in a Human Osteosarcoma Cell Line | p. 439 |
| Protease-Protease Inhibitor Balance in the Gastric Mucosa: Influence of Helicobacter pylori Infection | p. 445 |
| The Role of Bacterial and Host Proteinases in Periodontal Disease | p. 455 |
| Multifunctional Role of Proteases in Rheumatic Diseases | p. 467 |
| Evidence of Proteolytic Activation of Transforming Growth Factor [beta] in Synovial Fluid | p. 477 |
| Matrix Metalloproteinases and Tace Play a Role in the Pathogenesis of Endometriosis | p. 483 |
| Influence of Proliferation, Differentiation and Dedifferentiation Factors on the Expression of the Lysosomal Cysteine Proteinase Cathepsin L (CL) in Thyroid Cancer Cell Lines | p. 487 |
| Contributors | p. 497 |
| Index | p. 515 |
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