By: S. Narasimha Murthy (Editor), Howard I. Maibach (Editor)

Hardcover

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Discussing existing techniques, ongoing research, new approaches, and basic concepts in the treatment of nail diseases, Topical Nail Products and Ungual Drug Delivery summarizes the current knowledge and represents a jumping-off point for creating novel techniques of drug delivery across the nail.

A growing area of pharmaceutical research, the search for efficient delivery techniques that can cross the nail barrier has yielded several effective strategies, brought together in this book.

Topics Include

• Nail anatomy, physiology, diseases, and treatment
• Permeability of the nail plate
• Topical nail formulations
• Approaches to enhance ungual and trans-ungual drug delivery
• In vitro and in vivo models to evaluate topical nail formulations
• Nail sampling techniques
• Bioengineering of the nail
• Trans-ungual iontophoresis
• Pharmacokinetics of drugs in the nail apparatus
• Onychopharmacokinetics: proposed model insight
• Photodynamic therapy of nail diseases
• The nail as a surrogate for investigating drug use

Introduction. Permeability of Human Nail Plate. Topical Ungual Formulations. Chemicals to Enhance Trans-ungual Drug Permeation. In vitro / ex vivo Models for Evaluation of Trans-ungual Formulations. Physical Drug Delivery and Therapeutic Systems. Pharmacokinetics of Drug in the Nail Apparatus. Regulatory Aspects of Trans-ungual Formulations.

ISBN: 9781439811290
ISBN-10: 1439811296
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 282
Published: 26th September 2012
Dimensions (cm): 23.5 x 15.6
Weight (kg): 0.567