By: A.F. Dominiczak (Editor), J. M. C. Connell (Editor), F. Soubrier (Editor)

Hardcover

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This is a rapidly expanding research area, with most current publications existing as journal articles, or as single chapters in larger volumes. This will be one of the first books to bring all this information together into a comprehensive review volume, aimed at both researchers and clinicians.
Hypertension is a condition in humans which is characterized by persistently high arterial blood pressure (over 140/90 mm Hg). Affected individuals are at risk from heart disease, stroke and kidney failure. This important disease affects a huge number of people worldwide, and therefore the study of the disease is of vital clinical importance. Hypertension is a genetically determined disease, with many other contributing factors. Research has expanded rapidly in this area, particularly over the last decade, and there are continuing advances in our understanding of the disease.
Key Features
* One of the first books to look at this important disease which affects many individuals worldwide
* Looks at the study and the applications of molecular genetic approaches to this important disease
* Aimed at a wide audience from the clinician involved in this field
* Provides information on new strategies and developments in this expanding area of research

Hypertension as a Complex Trait Amenable to Genetic Analysis: Basic Strategies and Integrative Approaches
Improved Strategies for the Mapping of Quantitative Trait Loci in the Rat Model
Genetic and Cogenic Mapping of Loci for Blood Pressure and Blood Pressure-related phenotypes in the Rat
Molecular Genetics of Steroid Biosynthesis in Dahl Salt-Sensitive and Salt-resistant Rats: Linkage to the Control of Blood Pressure
Transgenic Rats and Hypertension
Mutating Genes to Study Hypertension
Monogenic Forms of Mineralocoticoid Hypertension
Teh Amiloride-sensitive Epithelial Na+ Channel: Structure and Function of a Key Molecule for Salt Homeostasis
The Study of Candidate Genes in Hypertension Using Tools of Molecular Biology and Genetic Epidemiology
Angiotensinogen and Hypertension
Pharmacogenomics in Arterial Hypertension
Molecular Genetics of Hypertension: Future Directions and Impact on Clinical Management
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9780122204302
ISBN-10: 0122204301
Series: Human Molecular Genetics
Audience: General
Format: Hardcover
Language: English
Number Of Pages: 320
Published: 20th October 1999
Dimensions (cm): 23.5 x 15.9  x 1.9
Weight (kg): 0.583