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Is it in Your Genes?

The Influence of Genes on Common Disorders and Diseases That Affect You and Your Family

Paperback

Published: 5th April 2004
For Ages: 15+ years old
Ships: 7 to 10 business days
RRP $46.99
$42.95

It is now clear that our risk of developing almost any disease is influenced by the genes with which we are born. One of the most important dividends of the Human Genome Project will be a much greater understanding of the influence of genes on disease and disorders in children (from asthma to autism) and adults (including heart disease, virtually all cancers, and Alzheimer's disease). The nature of genetic risks in families is becoming clearer and this book is written to help people understand them. Philip Reilly, a physician-geneticist, who has given hundreds of lectures on this subject, takes a user-friendly approach. Drawing on the many questions he has been asked (for example, My sister has multiple sclerosis. Am I at an increased risk?”), Reilly discusses over 90 common conditions, diseases, and disorders, arranged from conception to old age. In frank, non-technical terms, he makes clear what is known and not known about the genetic factors and, if your risk is elevated, what you might be able to do about it. This book is a uniquely valuable resource for anyone seeking more information about a family's disease heritage.

This book could do a great deal to enhance genetic literacy. It deserves to be read widely by students of human genetics at all levels, by primary care providers and practitioners in all specialties, by genetic counselors, and by anyone who has wondered whether they or their children are at risk for a disease affecting a family member. Journal of Clinical Investigation For clinicians, the impact of genetics on clinical practice outside the specialist area of the rare single gene disorders (or the Mendelian subsets of some of the common ones) has so far been small, but this will soon start to change and they will have to master the complexities of genetic and environmental interactions. Whilst Reilly's book is no substitute for proper professional development programmes, its clarity and its easy and accessible style will help them meet this challenge and provide sensible advice. Journal of the Royal Society of Medicine I very much enjoyed reading this book. It gives an up to date summary of the knowledge regarding genetic risk for common disease and disorders, is written very clearly and contains a large amount of information that is easy to find. To my knowledge, the information provided is factually correct and an excellent condensation of the primary literature (33 pages of primary literature and further information are provided at the back of the book). It tries to avoid jargon and by-and-large achieves this...In conclusion, this is a very readable book that I will recommend to friends and colleagues who are interested in the area of genetics, medicine and public health. Genetical Research

Prefacep. xi
Acknowledgmentsp. xiv
A Note about Technical Terminologyp. xv
Is It in Your Genes? Companion Web Sitep. xvi
Introduction: Genetic Medicinep. 1
Genes and Mutationsp. 7
Pregnancy
Infertilityp. 13
Endometriosisp. 16
Uterine Fibroidsp. 18
Consanguinityp. 20
Race and Ethnicityp. 22
Recurrent Pregnancy Lossp. 24
Preeclampsiap. 27
Twinningp. 28
Premature Birthsp. 30
Infancy
Congenital Malformations (Birth Defects)p. 33
Down Syndromep. 34
Spina Bifidap. 35
Congenital Heart Defectsp. 36
Cleft Lip and Cleft Palatep. 37
Pyloric Stenosisp. 38
Clubfootp. 39
Newborn Genetic Screeningp. 39
Deafnessp. 42
Sudden Infant Death Syndromep. 45
Childhood
Cerebral Palsyp. 47
Mental Retardationp. 49
Autismp. 53
Developmental Disabilitiesp. 56
Specific Reading Disability (Dyslexia)p. 56
Specific Language Impairmentp. 58
Attention Deficit Hyperactivity Disorderp. 60
Stutteringp. 62
Epilepsy (Seizures)p. 64
Juvenile Diabetesp. 68
Asthmap. 71
Eczemap. 73
Scoliosisp. 74
Staturep. 75
Strabismusp. 77
Eye Colorp. 78
Handednessp. 79
Adulthood
Heart Diseasesp. 81
Coronary Artery Disease (Atherosclerosis)p. 81
High Cholesterolp. 86
High Blood Pressurep. 87
Cardiomyopathyp. 90
Pulmonary Embolismp. 93
Sudden Deathp. 95
Aortic Aneurysmsp. 97
Atrial Fibrillationp. 99
Mitral Valve Prolapsep. 101
Longevityp. 102
Lung Diseasesp. 106
Chronic Obstructive Pulmonary Disease (COPD, Emphysema)p. 106
Sarcoidosisp. 108
Gastrointestinal Diseasesp. 110
Inflammatory Bowel Diseasep. 110
Peptic Ulcer Diseasep. 114
Celiac Disease (Gluten-sensitive Enteropathy)p. 116
Pancreatitisp. 118
Lactose Intolerance (Lactase Deficiency)p. 120
Appendicitisp. 121
Gallstones (Cholecystitis, Gallbladder Disease)p. 123
Endocrine Disordersp. 125
Adult-onset Diabetes (NIDDM, Diabetes Type II)p. 125
Obesityp. 128
Osteoporosisp. 133
Thyroid Diseasesp. 137
Infectious Diseasesp. 139
Susceptibility to Infectionp. 139
HIV/AIDSp. 145
Rheumatological Disordersp. 146
Rheumatoid Arthritisp. 146
Osteoarthritisp. 149
Goutp. 151
Lupusp. 153
Fibromyalgia Syndromep. 157
Skin Disordersp. 158
Atopic Dermatitisp. 158
Psoriasisp. 159
Baldnessp. 160
Cancerp. 162
Breast Cancerp. 162
Ovarian Cancerp. 169
Endometrial Cancerp. 172
Colon Cancerp. 173
Prostate Cancerp. 177
Kidney Cancerp. 180
Bladder Cancerp. 181
Stomach Cancerp. 183
Cancer of the Pancreasp. 185
Leukemiap. 188
Lymphomap. 190
Hodgkin's Diseasep. 190
Non-Hodgkin's Lymphomap. 191
Melanomap. 193
Lung Cancerp. 195
Brain Disordersp. 197
Strokep. 197
Alzheimer's Diseasep. 201
Migraine Headachesp. 204
Multiple Sclerosisp. 206
Parkinson's Diseasep. 208
Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)p. 212
Eye Disordersp. 214
Glaucomap. 214
Macular Degenerationp. 217
Mental Illnessp. 219
Schizophreniap. 219
Affective Disorder (Major Depression, Bipolar Illness)p. 223
Panic Disorderp. 228
Obsessive Compulsive Disorderp. 230
Anorexia Nervosap. 232
Human Behaviorp. 233
Alcoholismp. 233
Drug Addictionp. 236
Homosexualityp. 238
Conclusionp. 241
For Further Informationp. 245
Indexp. 279
Table of Contents provided by Rittenhouse. All Rights Reserved.

ISBN: 9780879697211
ISBN-10: 0879697210
Series: Handbooks
Audience: Tertiary; University or College
For Ages: 15+ years old
For Grades: 10+
Format: Paperback
Language: English
Number Of Pages: 304
Published: 5th April 2004
Dimensions (cm): 22.8 x 15.0  x 2.2
Weight (kg): 0.503